Spots Global Cancer Trial Database for Dose-Escalation Study of ABBV-838, an Antibody Drug Conjugate, in Subjects With Relapsed and Refractory Multiple Myeloma
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Trial Identification
Brief Title: Dose-Escalation Study of ABBV-838, an Antibody Drug Conjugate, in Subjects With Relapsed and Refractory Multiple Myeloma
Official Title: A Multicenter, Phase 1/1b, Open-Label, Dose-Escalation Study of ABBV-838, an Antibody Drug Conjugate, in Subjects With Relapsed and Refractory Multiple Myeloma
Study ID: NCT02462525
Conditions
Study Description
Brief Summary: This is a Phase 1/1b, open-label, dose-escalation study designed to evaluate the safety, pharmacokinetics, and to determine the recommended Phase 2 dose of ABBV-838 in subjects with relapsed and refractory multiple myeloma.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
The University of Chicago Medical Center /ID# 139403, Chicago, Illinois, United States
University of Michigan Medical Center /ID# 139402, Ann Arbor, Michigan, United States
Washington University School of Medicine /ID# 135708, Saint Louis, Missouri, United States
Mount Sinai Medical Center /ID# 133569, New York, New York, United States
The Sarah Cannon Research Institute /ID# 135814, Nashville, Tennessee, United States
CHRU de Lille, Hopital Claude Huriez /ID# 133634, Lille Cedex, , France
CHU de Nantes, Hotel Dieu - HME /ID# 133633, Nantes Cedex 1, , France
CHU de la miletrie, Centre d'investigation clinique /ID# 147542, Poitiers, , France
Universitaetsklinikum Koeln /ID# 141535, Cologne, , Germany
Universitaetklinikum Dresden /ID# 141860, Dresden, , Germany
Universitaetsklinikum Heidelberg /ID# 140046, Heidelberg, , Germany
Universitaetsklinikum Schleswig-Holstein /ID# 141534, Kiel, , Germany
Universitaetsklinikum Tuebingen /ID# 141074, Tuebingen, , Germany
Universitaetsklinikum Wuerzburg /ID# 141533, Wuerzburg, , Germany
Hospital Clinic de Barcelona /ID# 141643, Barcelona, , Spain
Hospital Universitario de la Princesa /ID# 140881, Madrid, , Spain
Hospital Universitario 12 de Octubre /ID# 140878, Madrid, , Spain
Clinica Universitaria de Navarra /ID# 141411, Pamplona-Navarra, , Spain
Hospital Clinico Universitario Salamanca /ID# 140880, Salamanca, , Spain
Contact Details
Name: AbbVie Inc.
Affiliation: AbbVie
Role: STUDY_DIRECTOR
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