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Spots Global Cancer Trial Database for A Real-World Study of Bispecific Antibodies in Multiple Myeloma

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Trial Identification

Brief Title: A Real-World Study of Bispecific Antibodies in Multiple Myeloma

Official Title: A Real-World Study of Bispecific Antibodies, Teclistamab and Elranatamab, for Patients With Multiple Myeloma

Study ID: NCT06359067

Study Description

Brief Summary: Bispecific antibody (BsAb) treatments, teclistamab and elranatamab, are newly available for patients with multiple myeloma who are refractory to all current drugs. The results are very encouraging but complicated adverse events, particularly infectious. This study analyzes survival data in patients treated with BsAb, as well as safety data, in particular the proportions and locations of infectious events. The results are compared to a control cohort. This study is multicentric on all the university hospitals of Paris (AP-HP).

Detailed Description: Bispecific antibody (BsAb) treatments, teclistamab and elranatamab, are newly available for patients with multiple myeloma who are refractory to all current drugs. The results are very encouraging but complicated adverse events, particularly infectious. This study analyzes survival data in patients treated with BsAb, as well as safety data, in particular the proportions and locations of infectious events. The results are compared to a control cohort. This study is multicentric on all the university hospitals of Paris (AP-HP).

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Assistance Publique - Hôpitaux de Paris (AP-HP), Paris, IDF, France

Contact Details

Name: Jeremie ZERBIT, PharmD

Affiliation: Pharmacy Department, Assistance Publique-Hopitaux de Paris, Université de Paris, Paris, France

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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