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Brief Title: A Study of VELCADE (Bortezomib) Melphalan-Prednisone (VMP) Compared to Daratumumab in Combination With VMP (D-VMP), in Participants With Previously Untreated Multiple Myeloma Who Are Ineligible for High-Dose Therapy (Asia Pacific Region)
Official Title: A Phase 3, Multicenter, Randomized, Controlled, Open-label Study of VELCADE (Bortezomib) Melphalan-Prednisone (VMP) Compared to Daratumumab in Combination With VMP (D-VMP), in Subjects With Previously Untreated Multiple Myeloma Who Are Ineligible for High-Dose Therapy (Asia Pacific Region)
Study ID: NCT03217812
Brief Summary: The purpose of this study is to determine if the addition of daratumumab to VELCADE-melphalan-prednisone (VMP) will improve very good partial response (VGPR) or better compared with VMP alone.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Beijing Chaoyang Hospital, Beijing, , China
Peking Union Medical College Hospital, Beijing, , China
Peking University First Hospital, Beijing, , China
Beijing Chaoyang Hospital, Beijing, , China
Peking University Third Hospital, Beijing, , China
The First Hospital of Jilin University, Changchun, , China
The Third Xiangya Hospital, Central South University, Changsha, , China
West China Hospital Si Chuan University, Chengdu, , China
Second Affiliated Hospital of Army Medical University, Chongqing, , China
Fujian Meidical University Union Hospital, Fuzhou, , China
Guangdong Provincial People's Hospital, Guangzhou, , China
The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, , China
Nanfang Hospital, Guangzhou, , China
First Affiliated Hospital Medical School of Zhejiang University, Hangzhou, , China
First affiliated Hospital of Zhejiang University, Hangzhou, , China
Harbin medical university cancer hospital, Harbin, , China
Nanjing Drum Tower Hospital, Nanjing, , China
Zhongda Hospital Southeast University, Nanjing, , China
Jiangsu Province Hospital, Nanjing, , China
Shanghai Changzheng Hospital, Shanghai, , China
Ruijin Hospital, Shanghai Jiao Tong University, Shanghai, , China
Shanghai Zhongshan Hospital, Shanghai, , China
Renji Hospital, Shanghai Jiaotong University School of Medicine, ShangHai, , China
First Affiliated Hospital SooChow University, Suzhou, , China
Tianjin cancer hospital, Tianjin, , China
Institute of Hematology and Blood Diseases Hospital, Tianjin, , China
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, , China
Tongji Hospital, Tongji Medical College of HUST, Wuhan, , China
Tangdu Hospital, Xian, , China
Henan Cancer Hospital, Zhengzhou, , China
Queen Mary Hospital University of Hong Kong, Hong Kong, , Hong Kong
Inje University Busan Paik Hospital, Busan, , Korea, Republic of
Gachon University Gil Medical Center, Incheon, , Korea, Republic of
Chonnam National University Hwasun Hospital, Jeollanam-do, , Korea, Republic of
Seoul National University Bundang Hospital, Seongnam-si, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
The Catholic University of Korea Seoul St. Mary's Hospital, Seoul, , Korea, Republic of
Ulsan University Hospital, Ulsan, , Korea, Republic of
Hospital Ampang, Ampang, , Malaysia
Hospital Pulau Pinang, George Town, , Malaysia
Hospital Queen Elizabeth, Kota Kinabalu, , Malaysia
National Taiwan University Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Taipei, , Taiwan
Chang Gung Memorial Hospital, Taoyuan, , Taiwan
Name: Janssen Research & Development, LLC Clinical Trial
Affiliation: Janssen Research & Development, LLC
Role: STUDY_DIRECTOR