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Brief Title: Study to Investigate Alternative Dosing Regimens of Belantamab Mafodotin in Participants With Relapsed or Refractory Multiple Myeloma
Official Title: A Phase 2, Randomized, Parallel, Open-label Study to Investigate the Safety, Efficacy, and Pharmacokinetics of Various Dosing Regimens of Single-agent Belantamab Mafodotin (GSK2857916) in Participants With Relapsed or Refractory Multiple Myeloma (DREAMM-14)
Study ID: NCT05064358
Brief Summary: This study aims to evaluate alternative dosing regimens of single-agent belantamab mafodotin in participants with relapsed or refractory multiple myeloma (RRMM) to determine if an improved overall benefit/risk profile can be achieved by modifying the belantamab mafodotin dose, schedule, or both.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
GSK Investigational Site, New Port Richey, Florida, United States
GSK Investigational Site, West Palm Beach, Florida, United States
GSK Investigational Site, Kansas City, Missouri, United States
GSK Investigational Site, New York, New York, United States
GSK Investigational Site, Chattanooga, Tennessee, United States
GSK Investigational Site, Nashville, Tennessee, United States
GSK Investigational Site, Houston, Texas, United States
GSK Investigational Site, Capital Federal, Buenos Aires, Argentina
GSK Investigational Site, Derqui, Pilar, Buenos Aires, Argentina
GSK Investigational Site, Rosario, Santa Fe, Argentina
GSK Investigational Site, Ciudad Autonoma de Buenos Aires, , Argentina
GSK Investigational Site, Ciudad Autonoma de Buenos Aires, , Argentina
GSK Investigational Site, Liverpool, New South Wales, Australia
GSK Investigational Site, Waratah, New South Wales, Australia
GSK Investigational Site, Woodville, South Australia, Australia
GSK Investigational Site, East Melbourne, Victoria, Australia
GSK Investigational Site, Salvador, Bahía, Brazil
GSK Investigational Site, Porto Alegre, Rio Grande Do Sul, Brazil
GSK Investigational Site, Joinville, Santa Catarina, Brazil
GSK Investigational Site, Rio de Janeiro, , Brazil
GSK Investigational Site, São Paulo, , Brazil
GSK Investigational Site, São Paulo, , Brazil
GSK Investigational Site, Oshawa, Ontario, Canada
GSK Investigational Site, Toronto, Ontario, Canada
GSK Investigational Site, Montreal, Quebec, Canada
GSK Investigational Site, Montréal, Quebec, Canada
GSK Investigational Site, Avignon cedex 9, , France
GSK Investigational Site, Le Mans, , France
GSK Investigational Site, Nice Cedex 2, , France
GSK Investigational Site, Orléans, , France
GSK Investigational Site, Saint-Priest en Jarez, , France
GSK Investigational Site, Cottbus, Brandenburg, Germany
GSK Investigational Site, Greifswald, Mecklenburg-Vorpommern, Germany
GSK Investigational Site, Dresden, Sachsen, Germany
GSK Investigational Site, Hamburg, , Germany
GSK Investigational Site, Athens, , Greece
GSK Investigational Site, Athens, , Greece
GSK Investigational Site, Haidari, Athens, , Greece
GSK Investigational Site, Rio/Patras, , Greece
GSK Investigational Site, Thessaloniki, , Greece
GSK Investigational Site, Nashik, Maharashtra, India
GSK Investigational Site, Ahmedabad, , India
GSK Investigational Site, Bangalore, , India
GSK Investigational Site, Hyderabad, , India
GSK Investigational Site, Jaipur, , India
GSK Investigational Site, Kerala, , India
GSK Investigational Site, Kolkata, , India
GSK Investigational Site, Kolkata, , India
GSK Investigational Site, Mumbai, , India
GSK Investigational Site, Pondicherry, , India
GSK Investigational Site, Pune, , India
GSK Investigational Site, Dublin, , Ireland
GSK Investigational Site, Dublin, , Ireland
GSK Investigational Site, Cona (FE), Emilia-Romagna, Italy
GSK Investigational Site, Meldola, Emilia-Romagna, Italy
GSK Investigational Site, Reggio Emilia, Emilia-Romagna, Italy
GSK Investigational Site, Rimini, Emilia-Romagna, Italy
GSK Investigational Site, Genova, Liguria, Italy
GSK Investigational Site, Ascoli Piceno, Marche, Italy
GSK Investigational Site, Alessandria, Piemonte, Italy
GSK Investigational Site, Cagliari, , Italy
GSK Investigational Site, Busan, , Korea, Republic of
GSK Investigational Site, Hwasun-gun, Jeollanam-do, , Korea, Republic of
GSK Investigational Site, Seoul, , Korea, Republic of
GSK Investigational Site, Seoul, , Korea, Republic of
GSK Investigational Site, Mexico City, Ciudad De Mexico, Mexico
GSK Investigational Site, Mexico, Ciudad De Mexico, Mexico
GSK Investigational Site, Bydgoszcz, , Poland
GSK Investigational Site, Gdansk, , Poland
GSK Investigational Site, Katowice, , Poland
GSK Investigational Site, Lublin, , Poland
GSK Investigational Site, Nowy Sacz, , Poland
GSK Investigational Site, Poznan, , Poland
GSK Investigational Site, Torun, , Poland
GSK Investigational Site, Walbrzych, , Poland
GSK Investigational Site, Warszawa, , Poland
GSK Investigational Site, Wroclaw, , Poland
GSK Investigational Site, Oviedo, Asturias, Spain
GSK Investigational Site, Albacete, , Spain
GSK Investigational Site, Barcelona, , Spain
GSK Investigational Site, Cordoba, , Spain
GSK Investigational Site, Gerona, , Spain
GSK Investigational Site, Lleida, , Spain
GSK Investigational Site, Terrassa (Barcelona), , Spain
GSK Investigational Site, Valencia, , Spain
GSK Investigational Site, Bern, , Switzerland
GSK Investigational Site, Taichung, , Taiwan
GSK Investigational Site, Taichung, , Taiwan
GSK Investigational Site, Tainan, , Taiwan
GSK Investigational Site, Taipei, , Taiwan
GSK Investigational Site, Taipei, , Taiwan
GSK Investigational Site, Bangkok, , Thailand
GSK Investigational Site, Bangkok, , Thailand
GSK Investigational Site, Chiang Mai, , Thailand
GSK Investigational Site, Khon Kaen, , Thailand
GSK Investigational Site, Stoke-on-Trent, Staffordshire, United Kingdom
GSK Investigational Site, Leicester, , United Kingdom
GSK Investigational Site, London, , United Kingdom
Name: GSK Clinical Trials
Affiliation: GlaxoSmithKline
Role: STUDY_DIRECTOR