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Brief Title: Combination of Lenalidomide and Dexamethasone in Treatment of Multiple Myeloma
Official Title: The Combination of Lenalidomide and Dexamethasone With or Without Intensification by High-dose Melphalan in the Treatment of Multiple Myeloma
Study ID: NCT01090089
Brief Summary: In this study for elderly myeloma patients lenalidomide plus low-dose dexamethasone until progression is being compared with age-adjusted tandem high-dose melphalan 140 mg/m² augmented by induction with 3 cycles of lenalidomide plus low-dose dexamethasone before transplantation and lenalidomide maintenance after transplantation.
Detailed Description:
Minimum Age: 60 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Universitätsklinikum Münster, Muenster, North Rhein Westfallen, Germany
Universitätsklinikum Aachen, Aachen, , Germany
Agirov Klinik, Berg, , Germany
HELIOS Klinikum Berlin-Buch, Berlin, , Germany
Evangelisches Krankenhaus Bielefeld, Bielefeld, , Germany
Klinikum Bremen-Mitte, Bremen, , Germany
Universitätsklinik Erlangen, Erlangen, , Germany
Universitätsklinikum Freiburg, Freiburg, , Germany
Universitätsklinikum der Ernst-Moritz-Arndt-Universität Greifswald -Anstalt öffentlichen Rechts-, Greifswald, , Germany
Universitätsklinikum Göttingen, Göttingen, , Germany
Universitätsklinikum Hamburg-Eppendorf, Hamburg, , Germany
Asklepios Klinik Altona, Hamburg, , Germany
Universitätsklinikum Schleswig-Holstein, Kiel, , Germany
Stiftungsklinikum Mittelrhein gGmbH, Koblenz, , Germany
Klinikum Landshut gemeinnützige GmbH, Landshut, , Germany
Stauferklinikum Schwäbisch Gmünd, Mutlangen, , Germany
Hämato-Onkologische Schwerpunktpraxis, München, , Germany
Onkologische Praxis Elisenhof, München, , Germany
Klinikum München Harlaching, München, , Germany
Klinikum rechts der Isar, München, , Germany
Klinikum Nord, Nürnberg, , Germany
Klinikum Oldenburg, Oldenburg, , Germany
Klinikum Ernst von Bergmann gGmbH, Potsdam, , Germany
Gemeinschaftspraxis für Innere Medizin, Hämatologie und Onkologie, Ravensburg, , Germany
Klinikum der Universität Regensburg, Regensburg, , Germany
Diakonie-Klinikum Stuttgart-Diakonissenkrankenhaus und Paulinenhilfe gGmbH, Stuttgart, , Germany
Robert-Bosch-Krankenhaus, Stuttgart, , Germany
Klinikum Traunstein, Traunstein, , Germany
Universitätsklinikum Ulm, Ulm, , Germany
HSK Dr. Horst-Schmidt-Kliniken gmbh, Wiesbaden, , Germany
Universitätsklinikum Würzburg, Würzburg, , Germany
Name: Christian Straka
Affiliation: Agirov Klinik
Role: PRINCIPAL_INVESTIGATOR