Spots Global Cancer Trial Database for An Investigational Immuno-therapy Study of Nivolumab, Pomalidomide and Dexamethasone Combinations in Patients With Multiple Myeloma
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Trial Identification
Brief Title: An Investigational Immuno-therapy Study of Nivolumab, Pomalidomide and Dexamethasone Combinations in Patients With Multiple Myeloma
Official Title: An Open-Label, Randomized Phase 3 Trial of Combinations of Nivolumab, Pomalidomide and Dexamethasone in Relapsed and Refractory Multiple Myeloma
Study ID: NCT02726581
Conditions
Study Description
Brief Summary: The purpose of this study is to evaluate the safety and effectiveness of several combination therapies for Multiple Myeloma. Upon entry into the study, patients will be randomized (assigned by chance) to receive either: Group 1: nivolumab, pomalidomide and dexamethasone OR Group 2: pomalidomide and dexamethasone OR Group 3: nivolumab, elotuzumab, pomalidomide and dexamethasone. Enrollment is closed for all groups.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Local Institution - 0020, Birmingham, Alabama, United States
Local Institution - 0160, Mobile, Alabama, United States
Local Institution - 0163, Fayetteville, Arkansas, United States
Local Institution - 0118, Bakersfield, California, United States
Local Institution - 0093, Corona, California, United States
Local Institution - 0016, Fountain Valley, California, United States
Local Institution - 0164, La Jolla, California, United States
UC San Diego Moores Cancer Ctr, La Jolla, California, United States
Local Institution - 0138, Los Angeles, California, United States
Local Institution - 0155, Los Angeles, California, United States
Local Institution - 0117, Redondo Beach, California, United States
Local Institution - 0092, Riverside, California, United States
Coastal Integrative Cancer Care, San Luis Obispo, California, United States
Local Institution - 0113, Santa Maria, California, United States
Colorado Blood Cancer Institute, Denver, Colorado, United States
Poudre Valley Health Care, Fort Collins, Colorado, United States
Local Institution - 0116, Grand Junction, Colorado, United States
Yale University School Of Medicine, New Haven, Connecticut, United States
Local Institution - 0147, Washington, District of Columbia, United States
Local Institution - 0011, Boynton Beach, Florida, United States
Florida Cancer Specialists S., Fort Myers, Florida, United States
Local Institution - 0114, Hollywood, Florida, United States
Cancer Specialists of North FL, Jacksonville, Florida, United States
Local Institution - 0082, Pensacola, Florida, United States
Local Institution - 0126, Saint Petersburg, Florida, United States
Local Institution - 0130, Tallahassee, Florida, United States
Local Institution - 0125, West Palm Beach, Florida, United States
Local Institution - 0119, Athens, Georgia, United States
Local Institution - 0009, Atlanta, Georgia, United States
Local Institution - 0024, Atlanta, Georgia, United States
Augusta University, Augusta, Georgia, United States
Local Institution - 0035, Chicago, Illinois, United States
Local Institution - 0111, Fort Wayne, Indiana, United States
Indiana University Cancer Ctr, Indianapolis, Indiana, United States
Local Institution - 0018, Bethesda, Maryland, United States
Local Institution - 0006, Baltimore, Massachusetts, United States
Local Institution - 0123, Worcester, Massachusetts, United States
Local Institution - 0150, Ypsilanti, Michigan, United States
Local Institution - 0137, Hattiesburg, Mississippi, United States
St. Louis Cancer Care, Llp, Bridgeton, Missouri, United States
Local Institution - 0128, Kansas City, Missouri, United States
Washington University, Saint Louis, Missouri, United States
Local Institution - 0049, Springfield, Missouri, United States
Local Institution - 0079, Lincoln, Nebraska, United States
Local Institution - 0076, Flemington, New Jersey, United States
Local Institution - 0002, Hackensack, New Jersey, United States
Local Institution - 0095, New Brunswick, New Jersey, United States
Local Institution - 0142, Paramus, New Jersey, United States
Local Institution - 0010, Buffalo, New York, United States
Broome Oncology LLC, Johnson City, New York, United States
Mount Sinai Medical Center, New York, New York, United States
Local Institution - 0017, New York, New York, United States
Local Institution - 0001, Durham, North Carolina, United States
Local Institution - 0096, Winston-Salem, North Carolina, United States
Local Institution - 0012, Columbus, Ohio, United States
University Of Oklahoma, Oklahoma City, Oklahoma, United States
Local Institution - 0145, Portland, Oregon, United States
Local Institution - 0136, Lancaster, Pennsylvania, United States
Local Institution - 0021, Philadelphia, Pennsylvania, United States
Local Institution - 0036, Sayre, Pennsylvania, United States
Local Institution - 0152, Greenville, South Carolina, United States
Local Institution - 0069, Germantown, Tennessee, United States
Tennessee Oncology, PLLC - SCRI - PPDS, Nashville, Tennessee, United States
Baylor Research Institute, Dallas, Texas, United States
Local Institution - 0044, Houston, Texas, United States
Local Institution - 0037, San Antonio, Texas, United States
Local Institution - 0046, Temple, Texas, United States
Local Institution - 0022, Ogden, Utah, United States
Local Institution - 0153, Salt Lake City, Utah, United States
Emily Couric Clinical Cancer Center, Charlottesville, Virginia, United States
Virginia Cancer Institute, Richmond, Virginia, United States
Local Institution - 0144, Seattle, Washington, United States
Local Institution - 0029, Linz, , Austria
Universitaetsklinik Salzburg, Salzburg, , Austria
Local Institution - 0026, Vienna, , Austria
Klinikum Wels-Grieskirchen Gmbh, Wels, , Austria
Wilhelminenspital, Wien, , Austria
Local Institution, Edmonton, Alberta, Canada
Local Institution, Vancouver, British Columbia, Canada
Local Institution - 0074, Toronto, Ontario, Canada
Local Institution - 0039, Montreal, Quebec, Canada
MUHC - Glen Site, Montreal, Quebec, Canada
Local Institution - 0154, Montreal, Quebec, Canada
Local Institution - 0157, Rimouski, Quebec, Canada
Local Institution, Quebec, , Canada
Interni hematologicka a onkologicka klinika, Brno, , Czechia
Klinika hematoonkologie, Ostrava-Poruba, , Czechia
I. interni klinika - klinika hematologie 1. LF UK a VFN v Praze, Praha 2, , Czechia
Local Institution, Aarhus, , Denmark
Local Institution, Odense, , Denmark
Local Institution - 0050, Berlin, , Germany
Universitaetsklinikum Carl Gustav Carus, Dresden, , Germany
Uniklinikum Duesseldorf, Duesseldorf, , Germany
Local Institution - 0135, Kiel, , Germany
Klinikum Der Johannes Gutenberg Universitaet Mainz, Mainz, , Germany
Local Institution - 0054, Ulm, , Germany
Alexandra General Hospital Of Athens, Athens, , Greece
Local Institution - 0087, Beer Sheva, , Israel
Local Institution, Jerusalem, , Israel
Local Institution, Petah Tikva, , Israel
Local Institution, Ramat-gan, , Israel
Local Institution, Tel Aviv, , Israel
Local Institution - 0042, Torino, Piemonte, Italy
Azienda Ospedaliero Universitaria Ospedali Riuniti Di Ancona, Ancona, , Italy
Local Institution - 0089, Bergamo, , Italy
A. O. U. Di Bologna, Policlinico S. Orsola Malpighi, Bologna, , Italy
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola (FC), , Italy
Azienda Ospedaliera Santa Maria Terni, Terni, , Italy
Local Institution, Oslo, , Norway
Local Institution - 0075, Stavanger, , Norway
Local Institution - 0132, Lisbon, Lisboa, Portugal
Local Institution, Porto, , Portugal
Local Institution - 0071, San Juan, , Puerto Rico
Local Institution - 0101, Pozuelo De Alarcon, Madrid, Spain
Local Institution - 0098, Badalona-Barcelona, , Spain
Local Institution - 0100, Barcelona, , Spain
Local Institution - 0097, Pamplona, , Spain
Local Institution - 0099, Salamanca, , Spain
Local Institution - 0064, Huddinge, , Sweden
Hopitaux Universitaires de Geneve, Geneve, , Switzerland
Local Institution - 0186, Istanbul, , Turkey
Contact Details
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR
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