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Spots Global Cancer Trial Database for Study of Mapatumumab in Combination With Bortezomib (Velcade) and Bortezomib Alone in Subjects With Relapsed or Refractory Multiple Myeloma

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Trial Identification

Brief Title: Study of Mapatumumab in Combination With Bortezomib (Velcade) and Bortezomib Alone in Subjects With Relapsed or Refractory Multiple Myeloma

Official Title: A Phase 2, Multi-Center, Open-Label, Randomized Study of Mapatumumab (TRM-1 [HGS1012], a Fully Human Monoclonal Antibody to TRAIL-R1) in Combination With Bortezomib (Velcade) and Bortezomib Alone in Subjects With Relapsed or Refractory Multiple Myeloma

Study ID: NCT00315757

Study Description

Brief Summary: The purpose of this study is to evaluate the efficacy (disease response) and safety of mapatumumab in combination with bortezomib and bortezomib alone in subjects with relapsed or refractory multiple myeloma (MM).

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mayo Clinic Arizona, Scottsdale, Arizona, United States

Scripps Clinic Medical Group, Inc., La Jolla, California, United States

Cancer and Blood Disorders Center, Lecanto, Florida, United States

University of Chicago, Chicago, Illinois, United States

Center for Cancer and Blood Disorders, Bethesda, Maryland, United States

Capitol Comprehensive Cancer Care Clinic, Jefferson City, Missouri, United States

Nebraska Methodist Cancer Center, Omaha, Nebraska, United States

Roswell Park Cancer Institute, Buffalo, New York, United States

Department of Haematology, Royal North Shore Hospital, St Leonards, New South Wales, Australia

Institute of Medical & Veterinary Science, Adelaide, South Australia, Australia

Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

Clinical Haematology & BMT, Alfred Hospital, Melbourne, Victoria, Australia

Tom Baker Cancer Center, Calgary, Alberta, Canada

Cross Cancer Institute, Edmonton, Alberta, Canada

Ottawa Health Research Institute - General Campus, Ottawa, Ontario, Canada

Notre Dame Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec, Canada

Bharath Hospital & Institute of Oncology, Mysore, Karnataka, India

Bangalore Institute of Oncology, Bangalore, , India

All India Institute of Medical Sciences, New Delhi, , India

Rajiv Gandhi Cancer Institute & Research Center, New Delhi, , India

Contact Details

Name: GSK Clinical Trials

Affiliation: GlaxoSmithKline

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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