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Spots Global Cancer Trial Database for Study of ACTR087 in Combination With SEA-BCMA in Subjects With Relapsed or Refractory Multiple Myeloma

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Trial Identification

Brief Title: Study of ACTR087 in Combination With SEA-BCMA in Subjects With Relapsed or Refractory Multiple Myeloma

Official Title: A Phase 1 Study of ACTR087, an Autologous T Cell Product, in Combination With SEA-BCMA, a Monoclonal Antibody, in Subjects With Relapsed or Refractory Multiple Myeloma

Study ID: NCT03266692

Interventions

ACTR087
SEA-BCMA

Study Description

Brief Summary: This is a phase 1, multi-center, single-arm, open-label study evaluating the safety, tolerability, and anti-myeloma activity of ACTR087 (an autologous T cell product) in combination with SEA-BCMA (a monoclonal antibody) in subjects with relapsed or refractory Multiple Myeloma.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mayo Clinic, Phoenix, Arizona, United States

Mayo Clinic, Jacksonville, Florida, United States

Indiana Blood and Marrow Transplantation, Indianapolis, Indiana, United States

Tufts Medical Center, Boston, Massachusetts, United States

Ohio State University Wexner Medical Center, Columbus, Ohio, United States

Baylor Scott & White, Dallas, Texas, United States

Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Contact Details

Name: Jessica Sachs, MD

Affiliation: Cogent Biosciences, Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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