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Spots Global Cancer Trial Database for A Safety and Efficacy Study Evaluating CTX120 in Subjects With Relapsed or Refractory Multiple Myeloma

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Trial Identification

Brief Title: A Safety and Efficacy Study Evaluating CTX120 in Subjects With Relapsed or Refractory Multiple Myeloma

Official Title: A Phase 1 Dose Escalation and Cohort Expansion Study of the Safety and Efficacy of Anti-BCMA Allogeneic CRISPR-Cas9-Engineered T Cells (CTX120) in Subjects With Relapsed or Refractory Multiple Myeloma

Study ID: NCT04244656

Interventions

CTX120

Study Description

Brief Summary: This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX120 in subjects with relapsed or refractory multiple myeloma.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Chicago, Chicago, Illinois, United States

Oregon Health and Science University, Portland, Oregon, United States

University of Pennsylvania, Philadelphia, Pennsylvania, United States

Sarah Cannon Research Institute, Nashville, Tennessee, United States

Royal Prince Alfred Hospital, Sydney, New South Wales, Australia

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

University Health Network, Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Institut Catala d'Oncologia Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain

Universidad de Navarra, Pamplona, Navarra, Spain

Hospital Universitario de Salamanca, Salamanca, , Spain

Contact Details

Name: Annie Weaver, PhD

Affiliation: CRISPR Therapeutics

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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