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Spots Global Cancer Trial Database for Autologous CD8+ T-cells Expressing an Anti-BCMA CAR in Patients With Myeloma

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Autologous CD8+ T-cells Expressing an Anti-BCMA CAR in Patients With Myeloma

Official Title: Combined Phase I-Phase II Study of Autologous CD8+ T-cells Transiently Expressing a Chimeric Antigen Receptor Directed to B-Cell Maturation Antigen in Patients With Multiple Myeloma

Study ID: NCT03448978

Study Description

Brief Summary: This Phase I/II study will test the safety and anti-myeloma activity of ascending doses of Descartes-08 (autologous CD8+ T-cells expressing an anti-BCMA chimeric antigen receptor) in eligible patients with active multiple myeloma.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

The Center for Cancer and Blood Disorders, Bethesda, Maryland, United States

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

Virgina Cancer Specialists, Fairfax, Virginia, United States

Contact Details

Name: Metin Kurtoglu, MD, PhD

Affiliation: Cartesian Therapeutics

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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