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Brief Title: A Study of Oral LGH447 in Patients With Relapsed and/or Refractory Multiple Myeloma
Official Title: A Multi-Center, Open-Label, Dose Escalation, Phase 1 Study of Oral LGH447 in Patients With Relapsed and/or Refractory Multiple Myeloma
Study ID: NCT01456689
Brief Summary: The primary purpose of this dose escalation study is to estimate the maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE) of LGH447 as a single agent when administered orally once daily to adult patients with Multiple Myeloma (MM).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Novartis Investigative Site, Chicago, Illinois, United States
Novartis Investigative Site, Ann Arbor, Michigan, United States
Novartis Investigative Site, Rochester, Minnesota, United States
Novartis Investigative Site, Houston, Texas, United States
Novartis Investigative Site, Heidelberg, , Germany
Novartis Investigative Site, Kiel, , Germany
Novartis Investigative Site, Singapore, , Singapore
Novartis Investigative Site, Salamanca, Castilla Y Leon, Spain
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR