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Brief Title: A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma
Official Title: An Exploratory Phase 1b/2a Multicenter, Open-Label, Novel-Novel Combination Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of CC-92480 (BMS-986348) in Novel Therapeutic Combinations in Participants With Relapsed or Refractory Multiple Myeloma
Study ID: NCT05372354
Brief Summary: The purpose of this study is to assess the safety, tolerability and preliminary effectiveness of CC-92480 (BMS-986348) in novel therapeutic combinations for the treatment of Relapsed or Refractory Multiple Myeloma (RRMM).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
UAB Comprehensive Cancer Center, Birmingham, Alabama, United States
Johns Hopkins Medicine - The Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
John Theurer Cancer Center at Hackensack UMC, Hackensack, New Jersey, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Alberta Health Services AHS - Foothills Medical Centre FMC, Calgary, Alberta, Canada
University of Alberta - Cross Cancer Institute, Edmonton, Alberta, Canada
University Health Network UHN - Princess Margaret Hospital PMH, Toronto, Ontario, Canada
Oslo University Hospital, Oslo, , Norway
Local Institution - 0011, Barcelona, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Hospital Universitario Marques de Valdecilla, Santander, , Spain
The Christie NHS Foundation Trust, Manchester, Greater Manchester, United Kingdom
Local Institution - 0001, Leicester, Leicestershire, United Kingdom
Local Institution - 0014, Liverpool, Merseyside, United Kingdom
Churchill Hospital, Oxford, Oxfordshire, United Kingdom
NIHR UCLH Clinical Research Facility, London, , United Kingdom
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR