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Brief Title: Descartes-11 in Multiple Myeloma
Official Title: Phase I Safety Study of Descartes-11 in Patients With Relapsed/Refractory Multiple Myeloma
Study ID: NCT03994705
Brief Summary: This Phase I/2 study will test the safety and anti-myeloma activity of ascending doses of Descartes-11 (autologous CD8+ T-cells expressing an anti-BCMA chimeric antigen receptor) in eligible patients with active multiple myeloma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Center for Cancer and Blood Disorders, Bethesda, Maryland, United States
Medical College of Wisconsin, Madison, Wisconsin, United States