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Brief Title: Daratumumab Combined With Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Multiple Myeloma Patients Presenting With Extramedullary Disease
Official Title: Daratumumab Combined With Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Multiple Myeloma Patients Presenting With Extramedullary Disease. The ANTARES Study
Study ID: NCT04166565
Brief Summary: This trial will try to establish the feasibility and efficacy of the combination of DaraVCD in Multiple Myeloma (MM) patients presenting with extramedullary disease (EMD). The study will be conducted as a Phase II trial. Forty patients will be included in the study cohort. All patients will be followed closely for toxicities and response assessment. After completion of treatment, patients will be followed every 6 months for survival until 5 years after enrolment
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Athens, Athens, , Greece
Anticancer Hospital of Thessaloniki, Thessaloníki, , Greece
University of Bologna, Bologna, , Italy
Univerity of Turin, Torino, , Italy
Ankara University, Ankara, , Turkey
Dokuz Eylul University, Balçova, , Turkey
Erciyes University, Kayseri, , Turkey
Marmara University, Pendik, , Turkey