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Brief Title: Study of BMS-986393 a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
Official Title: A Phase 2, Open-Label, Multicenter Study of BMS-986393, a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma (QUINTESSENTIAL)
Study ID: NCT06297226
Brief Summary: The purpose of this study is to evaluate the effectiveness and safety of BMS-986393 in participants with relapsed or refractory multiple myeloma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Local Institution - 0001, Birmingham, Alabama, United States
Local Institution - 0025, Gilbert, Arizona, United States
Local Institution - 0037, Little Rock, Arkansas, United States
UCLA Hematology/Oncology - Westwood (Building 200 Suite 214), Los Angeles, California, United States
Local Institution - 0018, San Francisco, California, United States
Colorado Blood Cancer Institute, Denver, Colorado, United States
Local Institution - 0045, Miami, Florida, United States
Local Institution - 0029, Tampa, Florida, United States
Local Institution - 0009, Atlanta, Georgia, United States
Local Institution - 0004, Atlanta, Georgia, United States
Local Institution - 0005, Chicago, Illinois, United States
Local Institution - 0056, Chicago, Illinois, United States
University of Iowa, Iowa City, Iowa, United States
Local Institution - 0016, Westwood, Kansas, United States
Local Institution - 0026, Saint Matthews, Kentucky, United States
Local Institution - 0039, Boston, Massachusetts, United States
Local Institution - 0036, Boston, Massachusetts, United States
Local Institution - 0033, Rochester, Minnesota, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Local Institution - 0034, New Brunswick, New Jersey, United States
Local Institution - 0046, Buffalo, New York, United States
Local Institution - 0002, New York, New York, United States
Local Institution - 0003, New York, New York, United States
Local Institution - 0031, Chapel Hill, North Carolina, United States
Local Institution - 0054, Cincinnati, Ohio, United States
Local Institution - 0032, Columbus, Ohio, United States
Local Institution - 0038, Portland, Oregon, United States
Local Institution - 0043, Nashville, Tennessee, United States
Local Institution - 0035, Dallas, Texas, United States
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Local Institution - 0055, San Antonio, Texas, United States
Local Institution - 0050, Salt Lake City, Utah, United States
Local Institution - 0011, Seattle, Washington, United States
University Hospital and UW Health Clinics, Madison, Wisconsin, United States
Local Institution - 0020, Calgary, Alberta, Canada
Local Institution - 0021, Montréal, Quebec, Canada
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR