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Brief Title: A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma
Official Title: A Multi-arm Phase 1b Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma
Study ID: NCT05050097
Brief Summary: The purpose of this study is to characterize the safety and tolerability of talquetamab when administered in different combination regimens and to identify the safe dose(s) of talquetamab combination regimens.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Alabama Birmingham, Birmingham, Alabama, United States
University of California San Francisco, San Francisco, California, United States
Colorado Blood Cancer Institute, Denver, Colorado, United States
Emory University, Atlanta, Georgia, United States
Indiana University, Indianapolis, Indiana, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Mt. Sinai School of Medicine, New York, New York, United States
Weill Cornell Medical College, New York, New York, United States
Levine Cancer Institute, Charlotte, North Carolina, United States
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Tennessee Oncology, Nashville, Tennessee, United States
Medical College Of Wisconsin, Milwaukee, Wisconsin, United States
St. Vincent's Hospital Melbourne, Fitzroy, , Australia
Alfred Health, Melbourne, , Australia
Gold Coast University Hospital, Southport, , Australia
Wollongong Hospital, Wollongong, , Australia
Cliniques Universitaires St-Luc, Brussel, , Belgium
UZA, Edegem, , Belgium
UZ Gent, Gent, , Belgium
UZ Leuven, Leuven, , Belgium
CHU Nantes, Nantes Cedex 1, , France
CHU de Bordeaux - Hospital Haut-Leveque, Pessac cedex, , France
Chu Rennes Hopital Pontchaillou, Rennes, , France
Institut Universitaire du cancer de Toulouse-Oncopole, TOULOUSE Cedex 9, , France
UMCG, Groningen, , Netherlands
Maastricht University Medical Centre, Maastricht, , Netherlands
UMCU, Utrecht, , Netherlands
University College Hospital London, London, , United Kingdom
The Christie Nhs Foundation Trust, Manchester, , United Kingdom
Churchill Hospital, Oxford, , United Kingdom
The Royal Marsden NHS Trust Sutton, Surrey, , United Kingdom
Name: Janssen Research & Development, LLC Clinical Trial
Affiliation: Janssen Research & Development, LLC
Role: STUDY_DIRECTOR