Spots Global Cancer Trial Database for Study of Iberdomide in People With Multiple Myeloma Who Have Had an Autologous Hematopoietic Stem Cell Transplant (AHCT)
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Trial Identification
Brief Title: Study of Iberdomide in People With Multiple Myeloma Who Have Had an Autologous Hematopoietic Stem Cell Transplant (AHCT)
Official Title: Phase II Multicenter Trial of Iberdomide as Maintenance Therapy for Multiple Myeloma Patients With Sub-Optimal Response After Autologous Hematopoietic Cell Transplantation or After Salvage Autologous Hematopoietic Cell Transplantation
Study ID: NCT05354557
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to see if iberdomide is a safe and effective maintenance therapy option for people with Multiple Myeloma (MM) who have had an Autologous Hematopoietic Stem Cell Transplant (AHCT) and have already had lenalidomide as maintenance therapy. Patients will receive iberdomide treatment beyond 12 months if they continue to derive benefit from the treatment and will continue until progression of disease or unacceptable toxicity. Follow-up will be as per standard of care for a patient on maintenance therapy, and patients will not require additional research samples.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Memorial Sloan Kettering Basking Ridge (Consent and Followup), Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Monmouth (Consent and Follow-Up only), Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen (Consent and Follow up), Montvale, New Jersey, United States
Memorial Sloan Kettering Suffolk-Commack (Consent and Follow up), Commack, New York, United States
Memorial Sloan Kettering Westchester (Consent and Follow Up), Harrison, New York, United States
Weill Cornell Medical College (Data Collection Only), New York, New York, United States
Memorial Sloan Kettering Cancer Center (All protocol activities), New York, New York, United States
Memorial Sloan Kettering Nassau (Consent and Followup), Rockville Centre, New York, United States
Contact Details
Name: Gunjan Shaw, MD
Affiliation: Memorial Sloan Kettering Cancer Center
Role: PRINCIPAL_INVESTIGATOR
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