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Brief Title: Exploring Outcomes and Characteristics of Myasthenia Gravis 2
Official Title: Exploring Outcomes and Characteristics of Myasthenia Gravis 2
Study ID: NCT06002945
Brief Summary: The goal of this prospective observational study is to create a network repository of clinical data and biological samples to help researchers learn more about myasthenia gravis.
Detailed Description: The EXPLORE-MG2 (EXPLoring Outcomes and chaRactEristics of Myasthenia Gravis 2) study is a multi-center natural history study of myasthenia gravis (MG), a rare autoimmune disease characterized by weakness of the voluntary muscles. MG has a prevalence of approximately 14-40 per 100,000 people in the United States. There is no cure for MG, however, understanding the disease is crucial to pave the way for development of new therapies and a deeper mechanistic understanding to improve patient outcomes. Thus, EXPLORE-MG2 aims to accomplish comprehensive clinical phenotyping linked to bio-specimen collection in an effort to better understand disease characteristics and identify treatment predictive and responsive biomarkers. The primary purpose of this project is to create a network repository of data and biological samples to help researchers learn more about myasthenia gravis.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of California-Irvine, Irvine, California, United States
Cedars Sinai Medical Center, Los Angeles, California, United States
Yale University, New Haven, Connecticut, United States
George Washington University, Washington, District of Columbia, United States
University of Chicago, Chicago, Illinois, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
University of North Carolina, Chapel Hill, North Carolina, United States
Duke University Medical Center, Durham, North Carolina, United States
Wake Forest University, Winston-Salem, North Carolina, United States
Medical University of South Carolina, Charleston, South Carolina, United States
Name: Richard Nowak, MD
Affiliation: Yale University
Role: PRINCIPAL_INVESTIGATOR
Name: Vern Juel, MD
Affiliation: Duke University
Role: PRINCIPAL_INVESTIGATOR