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Brief Title: Rhythmic Auditory Stimulation and Walking Speed in the 6-minute Walk Test
Official Title: Does Rhythmic Auditory Stimulation Influence Walking Speed in the 6-minute Walk Test in Patients With Myasthenia Gravis?
Study ID: NCT03905161
Brief Summary: The aim of this study is to investigate if rhythmic auditory stimulation can influence walking speed, during a 6MWT in patients with myasthenia gravis (MG).
Detailed Description: Background 1. The 6-minute walk test (6MWT) is widely used in the clinic to measure treatment efficacy and disease progression in patients with neuromuscular diseases and is found valid and reliable to measure decrease in walking speed. 2. Rhythmic auditory stimulation has repeatedly been shown to improve gait parameters in individuals with neurologic impairment. The aim of this study is to investigate if rhythmic auditory stimulation can influence walking speed, during a 6MWT in patients with myasthenia gravis. Patients with MG are asked to complete two 6MWTs separated by minimum 30 minutes of rest. Before the 6MWTs patient is instructed to walk 60 m as fast as possible, and their steps per minute (SPM) is recorded. When completing the 6MWTs, one of the tests is accompanied by music (m6MWT) with a beat per minute (BPM) corresponding to patients' SPM. The order of the 6MWTs is randomly decided by pre-ordered sealed envelopes.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Rigshospitalet, Copenhagen, , Denmark
Name: Linda K Andersen
Affiliation: Rigshospitalet, Denmark
Role: PRINCIPAL_INVESTIGATOR