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Brief Title: A Comparison of Fluconazole and Amphotericin B in the Treatment of Fungal Infections
Official Title: Fluconazole Versus Amphotericin B: A Prospective, Randomized, Multicenter Study for Therapy of Fungal Infection
Study ID: NCT00002277
Brief Summary: To compare the safety, tolerance and efficacy of fluconazole and amphotericin B as treatment for biopsy proven fungal infections in major organs, disseminated infection, suspected fungal infection and fungemia in adult neutropenic and non-neutropenic patients without AIDS, AIDS related complex (ARC), or extensive burns. HIV seropositive patients are allowed only if they also have a malignancy.
Detailed Description:
Minimum Age: 13 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Dr Layne Gentry, Houston, Texas, United States
Dr Temple Williams, Houston, Texas, United States
M D Anderson Cancer Ctr, Houston, Texas, United States