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Brief Title: Decitabine, Cytarabine, GCSF for Refractory AML/MDS
Official Title: A Phase II Study With Decitabine, Low Dose Cytarabine and G-CSF in High-risk Myelodysplastic Syndromes, Refractory Acute Myeloid Leukemia or Acute Myeloid Leukemia in Patients With Significant Co-morbidities.
Study ID: NCT00740181
Brief Summary: This study will determine the activity of decitabine, low dose cytarabine (ARA-C) and G-CSF for patients with myelodysplasia and leukemia.
Detailed Description: The primary objective of this study is to determine the feasibility and toxicity of decitabine, ARA-C and G-CSF for patients with myelodysplasia, refractory acute leukemia and poor performance status acute leukemia.
Minimum Age: 19 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Lifespan Hospitals, Providence, Rhode Island, United States
Name: James Butera
Affiliation: Brown University
Role: PRINCIPAL_INVESTIGATOR