Spots Global Cancer Trial Database for Research Tissue Bank
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Trial Identification
Brief Title: Research Tissue Bank
Official Title: Research Tissue Bank
Study ID: NCT00666549
Interventions
Study Description
Brief Summary: This study that will allow for the preservation and/or storage of a small portion one or more of the following tissues: * Peripheral blood * Bone marrow * Bone marrow biopsy * A phlebotomized unit of blood * Spleen cells * Toenail clippings This material will be used for the study of Myeloproliferative Disorders (MPD) by researchers. The goals of this research study are to understand the causes of MPDs, how to diagnose them more easily and how to treat them better. MPD is a disease affecting hematopoietic stem cells. Hematopoietic stem cells are cells that make blood cells. These stem cells grow in the center portion of the bones called bone marrow. Under some conditions, these cells are also found in blood. There are several diseases, which are classified as MPD. These include polycythemia vera (too many red blood cells), essential thrombocythemia (too many platelets), and idiopathic myelofibrosis (abnormal blood cells and fibers build up in the bone marrow). These syndromes carry a high risk of developing leukemia. It is important to continue to learn more about these blood cancers and to learn more about the effectiveness and potential side effects of various treatments.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Palo Alto Medical Foundation Research Institute, Palo Alto, California, United States
Weill Cornell University, Washington, District of Columbia, United States
University of Georgetown, Washington, District of Columbia, United States
University of Illinois at Chicago, Chicago, Illinois, United States
Johns Hopkins, Baltimore, Maryland, United States
Roswell Park, Buffalo, New York, United States
Mount Sinai Medical Center, New York, New York, United States
University of Pennsylvania, Philadelphia, Pennsylvania, United States
University of Utah, Salt Lake City, Utah, United States
Ospedali Riuniti di Bergamo, Bergamo, IL, Italy
University of Florence, Florence, IL, Italy
Contact Details
Name: Rona S Weinberg, PhD
Affiliation: Myeloproliferative Disorders-Research Consortium
Role: STUDY_CHAIR
Name: Lewis Silverman, MD
Affiliation: Icahn School of Medicine at Mount Sinai
Role: PRINCIPAL_INVESTIGATOR
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