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Spots Global Cancer Trial Database for Study of DISC-0974 in Participants With Myelofibrosis and Anemia

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Trial Identification

Brief Title: Study of DISC-0974 in Participants With Myelofibrosis and Anemia

Official Title: A Phase 1b/2a Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DISC-0974 in Participants With Myelofibrosis and Anemia

Study ID: NCT05320198

Interventions

DISC-0974

Study Description

Brief Summary: This phase 1b/2a open-label study will assess the safety, tolerability, pharmacokinetics and pharmacodynamics of DISC-0974 as well as categorize the effects on anemia response in subjects with myelofibrosis and anemia.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mayo Clinic Jacksonville, Jacksonville, Florida, United States

University of Michigan, Ann Arbor, Michigan, United States

Mayo Clinic Rochester, Rochester, Minnesota, United States

Washington University St.Louis, Saint Louis, Missouri, United States

Memorial Sloan Kettering Cancer Center, New York, New York, United States

Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina, United States

Gabrail Cancer Center Research, Canton, Ohio, United States

Cleveland Clinic, Cleveland, Ohio, United States

Oregon Health and Science University, Portland, Oregon, United States

Sargon Research - Pennsylvania Cancer Specialists and Research Center, Gettysburg, Pennsylvania, United States

University of Pennsylvania, Philadelphia, Pennsylvania, United States

MD Anderson, Houston, Texas, United States

University of Washington, Seattle, Washington, United States

Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Contact Details

Name: Will Savage, MD PhD

Affiliation: Disc Medicine

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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