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Spots Global Cancer Trial Database for Cyclophosphamide and Busulfan as Conditioning Regimen Before Allogeneic HSCT

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Trial Identification

Brief Title: Cyclophosphamide and Busulfan as Conditioning Regimen Before Allogeneic HSCT

Official Title: Cyclophosphamide-Busulfan Versus Busulfan-Cyclophosphamide as Conditioning Regimen Before Allogeneic Hematopoietic Stem Cell Transplantation for Leukemia: a Prospective Randomized Study to Assess Liver Toxicity

Study ID: NCT01779882

Study Description

Brief Summary: The aim of this study is to test the hypothesis, that the order of application of Busulfan (BU) and Cyclophosphamide (CY) has an impact on toxicity after allogeneic Hematopoietic stem cell transplantation (HSCT) and that CY-BU reduces liver toxicity compared to BU-CY.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University Hospital, Basel, Basel, , Switzerland

University Hospital Geneva, Geneva, , Switzerland

University Hospital Zurich, Zurich, , Switzerland

Contact Details

Name: Nathan Cantoni, MD

Affiliation: Kantonsspital Aarau, Switzerland

Role: STUDY_CHAIR

Name: Sabine Gerull, MD

Affiliation: University Hospital, Basel, Switzerland

Role: PRINCIPAL_INVESTIGATOR

Name: Gayathri Nair, MD

Affiliation: University Hospital, Zürich

Role: PRINCIPAL_INVESTIGATOR

Name: Yves Chalandon, MD

Affiliation: University Hospital Geneva, Switzerland

Role: PRINCIPAL_INVESTIGATOR

Name: Jakob Passweg, MD

Affiliation: University Hospital, Basel, Switzerland

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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