Spots Global Cancer Trial Database for IC Plus Low-dose Radiation Plus Cadonilimab in LANPC
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Trial Identification
Brief Title: IC Plus Low-dose Radiation Plus Cadonilimab in LANPC
Official Title: Induction Chemotherapy Combined With Low-dose Radiation Plus Cadonilimab in Loco-regionally Advanced Nasopharyngeal Carcinoma: a Multi-center, Open-label, Randomized Controlled Phase III Clinical Trial
Study ID: NCT05941741
Study Description
Brief Summary: This is a multi-center, open-label, randomized controlled phase III clinical trial in primary diagnosed loco-regionally advanced nasopharyngeal carcinoma (NPC) patients. The purpose of this study is to evaluate the efficacy of induction chemotherapy (IC) combined with low-dose radiation and immune checkpoint inhibitor (ICI) followed by concurrent chemoradiotherapy (CCRT) versus IC+CCRT, and compare the treatment-related adverse events and quality of life in two groups.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, China
The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
Jiangxi Cancer Hospital, Nanchang, Jiangxi, China
Contact Details
Name: Chong Zhao, MD, PhD
Affiliation: Sun Yat-sen University
Role: PRINCIPAL_INVESTIGATOR
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