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Spots Global Cancer Trial Database for Epstein-Barr Virus Antibody and Epstein-Barr Virus DNA for Nasopharyngeal Carcinoma Screening

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Trial Identification

Brief Title: Epstein-Barr Virus Antibody and Epstein-Barr Virus DNA for Nasopharyngeal Carcinoma Screening

Official Title: Parallel Controlled Study of Epstein-Barr Virus Antibody and Epstein-Barr Virus DNA for Nasopharyngeal Carcinoma Screening in the High-risk Population

Study ID: NCT05447169

Study Description

Brief Summary: The investigators intend to compare Epstein-Barr virus antibody and Epstein-Barr virus DNA screening efficacy in first-degree relatives of nasopharyngeal carcinoma patients.

Detailed Description: The investigators intend to test Epstein-Barr virus antibodies (Viral Capsid Antigen-immunoglobulin A, Epstein-Barr nuclear antigen 1-immunoglobulin A, early antigen-immunoglobulin A, Zta-immunoglobulin A, Rta-immunoglobulin G, Bnlf 2b) by ELISA and Epstein-Barr virus DNA by quantitative polymerase chain reaction, target sequencing and CRISPR-associated protein 12a in nasopharyngeal brushing and plasma of the same population at high-risk of nasopharyngeal carcinoma so as to determine the best method in nasopharyngeal carcinoma screening.

Eligibility

Minimum Age: 30 Years

Eligible Ages: ADULT

Sex: MALE

Healthy Volunteers: No

Locations

Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Contact Details

Name: Ming-Yuan Chen, MD, PhD

Affiliation: Sun Yat-sen University

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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