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Spots Global Cancer Trial Database for Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Official Title: A Phase III Randomized Trial of Chemotherapy With or Without Bevacizumab in Patients With Recurrent or Metastatic Head and Neck Cancer

Study ID: NCT00588770

Conditions

Neck Squamous Cell Carcinoma of Unknown Primary
Recurrent Hypopharyngeal Squamous Cell Carcinoma
Recurrent Laryngeal Squamous Cell Carcinoma
Recurrent Laryngeal Verrucous Carcinoma
Recurrent Lip and Oral Cavity Squamous Cell Carcinoma
Recurrent Neck Squamous Cell Carcinoma of Unknown Primary
Recurrent Oral Cavity Verrucous Carcinoma
Recurrent Oropharyngeal Squamous Cell Carcinoma
Recurrent Salivary Gland Carcinoma
Recurrent Sinonasal Squamous Cell Carcinoma
Salivary Gland Squamous Cell Carcinoma
Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7
Stage IV Major Salivary Gland Cancer AJCC v7
Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVA Laryngeal Verrucous Carcinoma AJCC v7
Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVA Major Salivary Gland Cancer AJCC v7
Stage IVA Oral Cavity Cancer AJCC v6 and v7
Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7
Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVB Laryngeal Verrucous Carcinoma AJCC v7
Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVB Major Salivary Gland Cancer AJCC v7
Stage IVB Oral Cavity Cancer AJCC v6 and v7
Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVB Sinonasal Squamous Cell Carcinoma AJCC v7
Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVC Laryngeal Verrucous Carcinoma AJCC v7
Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVC Major Salivary Gland Cancer AJCC v7
Stage IVC Oral Cavity Cancer AJCC v6 and v7
Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVC Sinonasal Squamous Cell Carcinoma AJCC v7
Tongue Carcinoma

Study Description

Brief Summary: This randomized phase III trial studies chemotherapy to see how well it works with or without bevacizumab in treating patients with head and neck squamous cell carcinoma that has come back (recurrent) or that has spread to other parts of the body (metastatic). Drugs used in chemotherapy, such as docetaxel, cisplatin, carboplatin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Monoclonal antibodies, such as bevacizumab, may interfere with the ability of tumor cells to grow and spread. Bevacizumab may also make tumor cells more sensitive to chemotherapy and stop the growth of head and neck cancer by blocking blood flow to the tumor. It is not yet known whether combination chemotherapy is more effective when given with or without bevacizumab in treating patients with head and neck squamous cell carcinoma.

Detailed Description: PRIMARY OBJECTIVES: I. To compare the overall survival of patients with recurrent or metastatic head and neck cancer treated with standard platinum-based chemotherapy with or without bevacizumab. SECONDARY OBJECTIVES: I. To assess toxicities with the addition of bevacizumab to each platinum-doublet (cisplatin/docetaxel, carboplatin/docetaxel, cisplatin/fluorouracil \[5-FU\], carboplatin/5-FU). II. To compare the objective response rates and the progression-free survival achieved with the above therapies. III. To collect blood samples before and after therapy for future correlative studies. IV. To collect tumor tissue samples available at baseline from prior diagnostic procedures for future correlative studies. OUTLINE: After the physician decides which chemotherapy doublet to use, patients are randomized to 1 of 2 treatment arms for that chemotherapy combination. ARM IA: Patients receive chemotherapy comprising docetaxel intravenously (IV) over 1 hour and cisplatin IV over 1-2 hours on day 1. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. ARM IB: Patients receive bevacizumab IV over 30-90 minutes on day 1 and docetaxel and cisplatin as in Arm IA. ARM IIA: Patients receive docetaxel IV over 1 hour and carboplatin IV over 30 minutes on day 1. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. ARM IIB: Patients receive bevacizumab as in arm IB and docetaxel and carboplatin as in Arm IIA. ARM IIIA: Patients receive cisplatin IV over 1-2 hours on day 1 and fluorouracil IV continuously on days 1-4. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. ARM IIIB: Patients receive bevacizumab as in Arm IB and cisplatin and fluorouracil as in Arm IIIA. ARM IVA: Patients receive carboplatin IV over 30 minutes on day 1 and fluorouracil IV continuously on days 1-4. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. ARM IVB: Patients receive bevacizumab as in Arm IB and carboplatin and fluorouracil as in Arm IVA. After completion of study treatment, patients are followed up every 3 months for 2 years and then every 6 months for 3 years.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Providence Hospital, Mobile, Alabama, United States

University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States

Fairbanks Memorial Hospital, Fairbanks, Alaska, United States

Mercy Hospital Fort Smith, Fort Smith, Arkansas, United States

NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro, Arkansas, United States

John L McClellan Memorial Veterans Hospital, Little Rock, Arkansas, United States

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

Kaiser Permanente-Anaheim, Anaheim, California, United States

Kaiser Permanente-Baldwin Park, Baldwin Park, California, United States

Kaiser Permanente-Bellflower, Bellflower, California, United States

Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California, United States

Mills-Peninsula Medical Center, Burlingame, California, United States

East Bay Radiation Oncology Center, Castro Valley, California, United States

Eden Hospital Medical Center, Castro Valley, California, United States

Valley Medical Oncology Consultants-Castro Valley, Castro Valley, California, United States

Epic Care-Dublin, Dublin, California, United States

Bay Area Breast Surgeons Inc, Emeryville, California, United States

Epic Care Partners in Cancer Care, Emeryville, California, United States

Kaiser Permanente-Fontana, Fontana, California, United States

Valley Medical Oncology Consultants-Fremont, Fremont, California, United States

Kaiser Permanente - Harbor City, Harbor City, California, United States

Kaiser Permanente-Irvine, Irvine, California, United States

UC San Diego Moores Cancer Center, La Jolla, California, United States

Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States

Kaiser Permanente West Los Angeles, Los Angeles, California, United States

Contra Costa Regional Medical Center, Martinez, California, United States

Memorial Medical Center, Modesto, California, United States

El Camino Hospital, Mountain View, California, United States

Sutter Cancer Research Consortium, Novato, California, United States

Highland General Hospital, Oakland, California, United States

Alta Bates Summit Medical Center - Summit Campus, Oakland, California, United States

Bay Area Tumor Institute, Oakland, California, United States

Hematology and Oncology Associates-Oakland, Oakland, California, United States

Tom K Lee Inc, Oakland, California, United States

Stanford Cancer Institute Palo Alto, Palo Alto, California, United States

VA Palo Alto Health Care System, Palo Alto, California, United States

Kaiser Permanente - Panorama City, Panorama City, California, United States

Valley Care Health System - Pleasanton, Pleasanton, California, United States

Valley Medical Oncology Consultants, Pleasanton, California, United States

Kaiser Permanente-Riverside, Riverside, California, United States

Saint Helena Hospital, Saint Helena, California, United States

Kaiser Permanente-San Diego Mission, San Diego, California, United States

Kaiser Permanente-San Diego Zion, San Diego, California, United States

San Diego VA Medical Center, San Diego, California, United States

California Pacific Medical Center-Pacific Campus, San Francisco, California, United States

Kaiser Permanente-San Marcos, San Marcos, California, United States

Doctors Medical Center- JC Robinson Regional Cancer Center, San Pablo, California, United States

Sutter Pacific Medical Foundation, Santa Rosa, California, United States

Sutter Solano Medical Center/Cancer Center, Vallejo, California, United States

Kaiser Permanente-Woodland Hills, Woodland Hills, California, United States

Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado, United States

The Medical Center of Aurora, Aurora, Colorado, United States

Boulder Community Hospital, Boulder, Colorado, United States

Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado, United States

Penrose-Saint Francis Healthcare, Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado, United States

Kaiser Permanente-Franklin, Denver, Colorado, United States

Porter Adventist Hospital, Denver, Colorado, United States

Colorado Blood Cancer Institute, Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown, Denver, Colorado, United States

SCL Health Saint Joseph Hospital, Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose, Denver, Colorado, United States

Rose Medical Center, Denver, Colorado, United States

Western States Cancer Research NCORP, Denver, Colorado, United States

Mercy Medical Center, Durango, Colorado, United States

Southwest Oncology PC, Durango, Colorado, United States

Mountain Blue Cancer Care Center - Swedish, Englewood, Colorado, United States

Swedish Medical Center, Englewood, Colorado, United States

Poudre Valley Hospital, Fort Collins, Colorado, United States

Mountain Blue Cancer Care Center, Golden, Colorado, United States

Saint Mary's Hospital and Regional Medical Center, Grand Junction, Colorado, United States

Banner North Colorado Medical Center, Greeley, Colorado, United States

Rocky Mountain Cancer Centers-Greenwood Village, Greenwood Village, Colorado, United States

Kaiser Permanente-Rock Creek, Lafayette, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado, United States

Saint Anthony Hospital, Lakewood, Colorado, United States

Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado, United States

Littleton Adventist Hospital, Littleton, Colorado, United States

Kaiser Permanente-Lone Tree, Lone Tree, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge, Lone Tree, Colorado, United States

Sky Ridge Medical Center, Lone Tree, Colorado, United States

Longmont United Hospital, Longmont, Colorado, United States

Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado, United States

Banner McKee Medical Center, Loveland, Colorado, United States

Parker Adventist Hospital, Parker, Colorado, United States

Rocky Mountain Cancer Centers-Parker, Parker, Colorado, United States

Saint Mary Corwin Medical Center, Pueblo, Colorado, United States

Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado, United States

North Suburban Medical Center, Thornton, Colorado, United States

Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado, United States

SCL Health Lutheran Medical Center, Wheat Ridge, Colorado, United States

University of Connecticut, Farmington, Connecticut, United States

Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut, United States

The Hospital of Central Connecticut, New Britain, Connecticut, United States

Yale University, New Haven, Connecticut, United States

Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut, United States

Bayhealth Hospital Kent Campus, Dover, Delaware, United States

Beebe Medical Center, Lewes, Delaware, United States

Christiana Gynecologic Oncology LLC, Newark, Delaware, United States

Delaware Clinical and Laboratory Physicians PA, Newark, Delaware, United States

Helen F Graham Cancer Center, Newark, Delaware, United States

Medical Oncology Hematology Consultants PA, Newark, Delaware, United States

Christiana Care Health System-Christiana Hospital, Newark, Delaware, United States

Beebe Health Campus, Rehoboth Beach, Delaware, United States

TidalHealth Nanticoke / Allen Cancer Center, Seaford, Delaware, United States

Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware, United States

MedStar Georgetown University Hospital, Washington, District of Columbia, United States

George Washington University Medical Center, Washington, District of Columbia, United States

Boca Raton Regional Hospital, Boca Raton, Florida, United States

Holy Cross Hospital, Fort Lauderdale, Florida, United States

Broward Health Medical Center, Fort Lauderdale, Florida, United States

Florida Cancer Specialists-Gainesville Cancer Center, Gainesville, Florida, United States

University of Florida Health Science Center - Gainesville, Gainesville, Florida, United States

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida, United States

Baptist MD Anderson Cancer Center, Jacksonville, Florida, United States

Jupiter Medical Center, Jupiter, Florida, United States

Mount Sinai Medical Center, Miami Beach, Florida, United States

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida, United States

Memorial Hospital West, Pembroke Pines, Florida, United States

Sacred Heart Hospital, Pensacola, Florida, United States

Space Coast Cancer Centers-Titusville, Titusville, Florida, United States

Cleveland Clinic-Weston, Weston, Florida, United States

Emory University Hospital Midtown, Atlanta, Georgia, United States

Piedmont Hospital, Atlanta, Georgia, United States

Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, United States

Atlanta Regional CCOP, Atlanta, Georgia, United States

Emory Saint Joseph's Hospital, Atlanta, Georgia, United States

Northside Hospital, Atlanta, Georgia, United States

WellStar Cobb Hospital, Austell, Georgia, United States

John B Amos Cancer Center, Columbus, Georgia, United States

Atlanta VA Medical Center, Decatur, Georgia, United States

Dekalb Medical Center, Decatur, Georgia, United States

Piedmont Fayette Hospital, Fayetteville, Georgia, United States

Northeast Georgia Medical Center-Gainesville, Gainesville, Georgia, United States

Northside Hospital - Gwinnett, Lawrenceville, Georgia, United States

Wellstar Kennestone Hospital, Marietta, Georgia, United States

Southern Regional Medical Center, Riverdale, Georgia, United States

Harbin Clinic Medical Oncology and Clinical Research, Rome, Georgia, United States

Low Country Cancer Care, Savannah, Georgia, United States

Memorial Health University Medical Center, Savannah, Georgia, United States

Summit Cancer Care-Memorial, Savannah, Georgia, United States

Pali Momi Medical Center, 'Aiea, Hawaii, United States

Hawaii Cancer Care Inc - Waterfront Plaza, Honolulu, Hawaii, United States

Queen's Medical Center, Honolulu, Hawaii, United States

Straub Clinic and Hospital, Honolulu, Hawaii, United States

University of Hawaii Cancer Center, Honolulu, Hawaii, United States

Queen's Cancer Center - Kuakini, Honolulu, Hawaii, United States

The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii, United States

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii, United States

Maui Memorial Medical Center, Wailuku, Hawaii, United States

Pacific Cancer Institute of Maui, Wailuku, Hawaii, United States

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho, United States

Saint Luke's Cancer Institute - Boise, Boise, Idaho, United States

Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho, United States

Saint Luke's Cancer Institute - Meridian, Meridian, Idaho, United States

Saint Luke's Cancer Institute - Nampa, Nampa, Idaho, United States

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho, United States

Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho, United States

Rush - Copley Medical Center, Aurora, Illinois, United States

Mac Neal Hospital, Berwyn, Illinois, United States

OSF Saint Joseph Medical Center, Bloomington, Illinois, United States

Illinois CancerCare-Bloomington, Bloomington, Illinois, United States

Graham Hospital Association, Canton, Illinois, United States

Illinois CancerCare-Canton, Canton, Illinois, United States

Memorial Hospital of Carbondale, Carbondale, Illinois, United States

Illinois CancerCare-Carthage, Carthage, Illinois, United States

Memorial Hospital, Carthage, Illinois, United States

Centralia Oncology Clinic, Centralia, Illinois, United States

Mount Sinai Hospital Medical Center, Chicago, Illinois, United States

Hematology and Oncology Associates, Chicago, Illinois, United States

Northwestern University, Chicago, Illinois, United States

John H Stroger Jr Hospital of Cook County, Chicago, Illinois, United States

University of Illinois, Chicago, Illinois, United States

Presence Resurrection Medical Center, Chicago, Illinois, United States

Weiss Memorial Hospital, Chicago, Illinois, United States

UChicago Medicine Comprehensive Cancer Center - Saint Joseph Hospital, Chicago, Illinois, United States

Carle at The Riverfront, Danville, Illinois, United States

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois, United States

Decatur Memorial Hospital, Decatur, Illinois, United States

Heartland Cancer Research NCORP, Decatur, Illinois, United States

Advocate Good Samaritan Hospital, Downers Grove, Illinois, United States

Carle Physician Group-Effingham, Effingham, Illinois, United States

Crossroads Cancer Center, Effingham, Illinois, United States

Elmhurst Memorial Hospital, Elmhurst, Illinois, United States

Eureka Hospital, Eureka, Illinois, United States

Illinois CancerCare-Eureka, Eureka, Illinois, United States

NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois, United States

Galesburg Cottage Hospital, Galesburg, Illinois, United States

Illinois CancerCare-Galesburg, Galesburg, Illinois, United States

Western Illinois Cancer Treatment Center, Galesburg, Illinois, United States

NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois, United States

Ingalls Memorial Hospital, Harvey, Illinois, United States

Illinois CancerCare-Havana, Havana, Illinois, United States

Mason District Hospital, Havana, Illinois, United States

Hematology Oncology Associates of Illinois-Highland Park, Highland Park, Illinois, United States

NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois, United States

Hinsdale Hematology Oncology Associates Incorporated, Hinsdale, Illinois, United States

Hopedale Medical Complex - Hospital, Hopedale, Illinois, United States

Midwest Center for Hematology Oncology, Joliet, Illinois, United States

Duly Health and Care Joliet, Joliet, Illinois, United States

Presence Saint Mary's Hospital, Kankakee, Illinois, United States

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois, United States

AMITA Health Adventist Medical Center, La Grange, Illinois, United States

AMG Libertyville - Oncology, Libertyville, Illinois, United States

Illinois CancerCare-Macomb, Macomb, Illinois, United States

Mcdonough District Hospital, Macomb, Illinois, United States

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois, United States

Loyola University Medical Center, Maywood, Illinois, United States

Garneau, Stewart C MD (UIA Investigator), Moline, Illinois, United States

Porubcin, Michael MD (UIA Investigator), Moline, Illinois, United States

Spector, David MD (UIA Investigator), Moline, Illinois, United States

Trinity Medical Center, Moline, Illinois, United States

Holy Family Medical Center, Monmouth, Illinois, United States

Illinois CancerCare-Monmouth, Monmouth, Illinois, United States

Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States

Illinois Cancer Specialists-Niles, Niles, Illinois, United States

Bromenn Regional Medical Center, Normal, Illinois, United States

Carle Cancer Institute Normal, Normal, Illinois, United States

Illinois CancerCare-Community Cancer Center, Normal, Illinois, United States

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois, United States

Ottawa Regional Hospital and Healthcare Center, Ottawa, Illinois, United States

Radiation Oncology of Northern Illinois, Ottawa, Illinois, United States

Illinois CancerCare-Pekin, Pekin, Illinois, United States

OSF Saint Francis Radiation Oncology at Pekin, Pekin, Illinois, United States

Pekin Hospital, Pekin, Illinois, United States

Proctor Hospital, Peoria, Illinois, United States

Illinois CancerCare-Peoria, Peoria, Illinois, United States

OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois, United States

Methodist Medical Center of Illinois, Peoria, Illinois, United States

OSF Saint Francis Medical Center, Peoria, Illinois, United States

Illinois CancerCare-Peru, Peru, Illinois, United States

Illinois Valley Hospital, Peru, Illinois, United States

Valley Radiation Oncology, Peru, Illinois, United States

Illinois CancerCare-Princeton, Princeton, Illinois, United States

Perry Memorial Hospital, Princeton, Illinois, United States

West Suburban Medical Center, River Forest, Illinois, United States

Swedish American Hospital, Rockford, Illinois, United States

UW Health Carbone Cancer Center Rockford, Rockford, Illinois, United States

Hematology Oncology Associates of Illinois - Skokie, Skokie, Illinois, United States

Illinois CancerCare-Spring Valley, Spring Valley, Illinois, United States

Saint Margaret's Hospital, Spring Valley, Illinois, United States

Central Illinois Hematology Oncology Center, Springfield, Illinois, United States

Memorial Medical Center, Springfield, Illinois, United States

Carle Cancer Center, Urbana, Illinois, United States

The Carle Foundation Hospital, Urbana, Illinois, United States

Rush-Copley Healthcare Center, Yorkville, Illinois, United States

Elkhart Clinic, Elkhart, Indiana, United States

Michiana Hematology Oncology PC-Elkhart, Elkhart, Indiana, United States

Elkhart General Hospital, Elkhart, Indiana, United States

Fort Wayne Medical Oncology and Hematology Inc-Parkview, Fort Wayne, Indiana, United States

Sidney and Lois Eskenazi Hospital, Indianapolis, Indiana, United States

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana, United States

Community Howard Regional Health, Kokomo, Indiana, United States

IU Health La Porte Hospital, La Porte, Indiana, United States

IU Health Arnett Cancer Care, Lafayette, Indiana, United States

Franciscan Saint Anthony Health-Michigan City, Michigan City, Indiana, United States

Woodland Cancer Care Center, Michigan City, Indiana, United States

Cancer Care Partners LLC, Mishawaka, Indiana, United States

Memorial Regional Cancer Center Day Road, Mishawaka, Indiana, United States

Michiana Hematology Oncology PC-Mishawaka, Mishawaka, Indiana, United States

Saint Joseph Regional Medical Center-Mishawaka, Mishawaka, Indiana, United States

IU Health Ball Memorial Hospital, Muncie, Indiana, United States

Michiana Hematology Oncology PC-Plymouth, Plymouth, Indiana, United States

Memorial Hospital of South Bend, South Bend, Indiana, United States

Michiana Hematology Oncology PC-South Bend, South Bend, Indiana, United States

South Bend Clinic, South Bend, Indiana, United States

Northern Indiana Cancer Research Consortium, South Bend, Indiana, United States

Michiana Hematology Oncology PC-Westville, Westville, Indiana, United States

Mary Greeley Medical Center, Ames, Iowa, United States

McFarland Clinic - Ames, Ames, Iowa, United States

Constantinou, Costas L MD (UIA Investigator), Bettendorf, Iowa, United States

University of Iowa Healthcare Cancer Services Quad Cities, Bettendorf, Iowa, United States

McFarland Clinic - Boone, Boone, Iowa, United States

Mercy Hospital, Cedar Rapids, Iowa, United States

Oncology Associates at Mercy Medical Center, Cedar Rapids, Iowa, United States

Mercy Cancer Center-West Lakes, Clive, Iowa, United States

Mission Cancer and Blood - West Des Moines, Clive, Iowa, United States

Alegent Health Mercy Hospital, Council Bluffs, Iowa, United States

Mercy Capitol, Des Moines, Iowa, United States

Iowa Methodist Medical Center, Des Moines, Iowa, United States

Iowa-Wide Oncology Research Coalition NCORP, Des Moines, Iowa, United States

Mission Cancer and Blood - Des Moines, Des Moines, Iowa, United States

Mercy Medical Center - Des Moines, Des Moines, Iowa, United States

Mission Cancer and Blood - Laurel, Des Moines, Iowa, United States

Iowa Lutheran Hospital, Des Moines, Iowa, United States

McFarland Clinic - Trinity Cancer Center, Fort Dodge, Iowa, United States

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa, United States

McFarland Clinic - Jefferson, Jefferson, Iowa, United States

McFarland Clinic - Marshalltown, Marshalltown, Iowa, United States

Mercy Medical Center - North Iowa, Mason City, Iowa, United States

Ottumwa Regional Health Center, Ottumwa, Iowa, United States

Siouxland Regional Cancer Center, Sioux City, Iowa, United States

Mercy Medical Center-Sioux City, Sioux City, Iowa, United States

Saint Luke's Regional Medical Center, Sioux City, Iowa, United States

Methodist West Hospital, West Des Moines, Iowa, United States

Mercy Medical Center-West Lakes, West Des Moines, Iowa, United States

Cancer Center of Kansas - Chanute, Chanute, Kansas, United States

Cancer Center of Kansas - Dodge City, Dodge City, Kansas, United States

Cancer Center of Kansas - El Dorado, El Dorado, Kansas, United States

Cancer Center of Kansas - Fort Scott, Fort Scott, Kansas, United States

Cancer Center of Kansas-Independence, Independence, Kansas, United States

Providence Medical Center, Kansas City, Kansas, United States

Cancer Center of Kansas-Kingman, Kingman, Kansas, United States

Lawrence Memorial Hospital, Lawrence, Kansas, United States

Cancer Center of Kansas-Liberal, Liberal, Kansas, United States

Cancer Center of Kansas-Manhattan, Manhattan, Kansas, United States

Cancer Center of Kansas - McPherson, McPherson, Kansas, United States

Cancer Center of Kansas - Newton, Newton, Kansas, United States

Menorah Medical Center, Overland Park, Kansas, United States

Saint Luke's South Hospital, Overland Park, Kansas, United States

Cancer Center of Kansas - Parsons, Parsons, Kansas, United States

Kansas City NCI Community Oncology Research Program, Prairie Village, Kansas, United States

Cancer Center of Kansas - Pratt, Pratt, Kansas, United States

Cancer Center of Kansas - Salina, Salina, Kansas, United States

Advent Health - Shawnee Mission Medical Center, Shawnee Mission, Kansas, United States

Cancer Center of Kansas - Wellington, Wellington, Kansas, United States

Associates In Womens Health, Wichita, Kansas, United States

Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas, United States

Ascension Via Christi Hospitals Wichita, Wichita, Kansas, United States

Cancer Center of Kansas - Wichita, Wichita, Kansas, United States

Wesley Medical Center, Wichita, Kansas, United States

Wichita NCI Community Oncology Research Program, Wichita, Kansas, United States

Cancer Center of Kansas - Winfield, Winfield, Kansas, United States

Our Lady Bellefonte Hospital, Ashland, Kentucky, United States

Flaget Memorial Hospital, Bardstown, Kentucky, United States

Commonwealth Cancer Center-Corbin, Corbin, Kentucky, United States

Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky, United States

Saint Joseph Hospital East, Lexington, Kentucky, United States

University of Kentucky/Markey Cancer Center, Lexington, Kentucky, United States

Jewish Hospital, Louisville, Kentucky, United States

Saints Mary and Elizabeth Hospital, Louisville, Kentucky, United States

UofL Health Medical Center Northeast, Louisville, Kentucky, United States

Jewish Hospital Medical Center South, Shepherdsville, Kentucky, United States

Baton Rouge General Medical Center, Baton Rouge, Louisiana, United States

Hematology/Oncology Clinic PLLC, Baton Rouge, Louisiana, United States

Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, United States

West Jefferson Medical Center, Marrero, Louisiana, United States

Robert Veith MD LLC, Metairie, Louisiana, United States

Ochsner LSU Health Monroe Medical Center, Monroe, Louisiana, United States

Louisiana State University Health Science Center, New Orleans, Louisiana, United States

Tulane University School of Medicine, New Orleans, Louisiana, United States

University Medical Center New Orleans, New Orleans, Louisiana, United States

LSU Health Sciences Center at Shreveport, Shreveport, Louisiana, United States

Highland Clinic, Shreveport, Louisiana, United States

Harold Alfond Center for Cancer Care, Augusta, Maine, United States

Eastern Maine Medical Center, Bangor, Maine, United States

Greater Baltimore Medical Center, Baltimore, Maryland, United States

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland, United States

Christiana Care - Union Hospital, Elkton, Maryland, United States

Frederick Memorial Hospital, Frederick, Maryland, United States

Sturdy Memorial Hospital, Attleboro, Massachusetts, United States

Beverly Hospital, Beverly, Massachusetts, United States

Tufts Medical Center, Boston, Massachusetts, United States

Boston Medical Center, Boston, Massachusetts, United States

Addison Gilbert Hospital, Gloucester, Massachusetts, United States

Holy Family Hospital, Methuen, Massachusetts, United States

Berkshire Medical Center - Cancer Center, Pittsfield, Massachusetts, United States

Baystate Medical Center, Springfield, Massachusetts, United States

Michigan Cancer Research Consortium NCORP, Ann Arbor, Michigan, United States

Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan, United States

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

Bronson Battle Creek, Battle Creek, Michigan, United States

Spectrum Health Big Rapids Hospital, Big Rapids, Michigan, United States

Beaumont Hospital - Dearborn, Dearborn, Michigan, United States

Ascension Saint John Hospital, Detroit, Michigan, United States

OSF Saint Francis Hospital and Medical Group, Escanaba, Michigan, United States

Beaumont Hospital - Farmington Hills, Farmington Hills, Michigan, United States

Genesys Hurley Cancer Institute, Flint, Michigan, United States

Hurley Medical Center, Flint, Michigan, United States

Genesys Regional Medical Center-West Flint Campus, Flint, Michigan, United States

Cancer Research Consortium of West Michigan NCORP, Grand Rapids, Michigan, United States

Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids, Michigan, United States

Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan, United States

Green Bay Oncology - Iron Mountain, Iron Mountain, Michigan, United States

Allegiance Health, Jackson, Michigan, United States

Bronson Methodist Hospital, Kalamazoo, Michigan, United States

West Michigan Cancer Center, Kalamazoo, Michigan, United States

Borgess Medical Center, Kalamazoo, Michigan, United States

University of Michigan Health - Sparrow Lansing, Lansing, Michigan, United States

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan, United States

UP Health System Marquette, Marquette, Michigan, United States

Mercy Health Partners-Hackley Campus, Muskegon, Michigan, United States

Trinity Health Muskegon Hospital, Muskegon, Michigan, United States

Corewell Health Lakeland Hospitals - Niles Hospital, Niles, Michigan, United States

Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan, United States

Lake Huron Medical Center, Port Huron, Michigan, United States

Corewell Health Reed City Hospital, Reed City, Michigan, United States

William Beaumont Hospital-Royal Oak, Royal Oak, Michigan, United States

Ascension Saint Mary's Hospital, Saginaw, Michigan, United States

Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center, Saint Joseph, Michigan, United States

Corewell Health Lakeland Hospitals - Saint Joseph Hospital, Saint Joseph, Michigan, United States

Munson Medical Center, Traverse City, Michigan, United States

William Beaumont Hospital - Troy, Troy, Michigan, United States

Saint John Macomb-Oakland Hospital, Warren, Michigan, United States

University of Michigan Health - West, Wyoming, Michigan, United States

Medini, Eitan MD (UIA Investigator), Alexandria, Minnesota, United States

Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota, United States

Fairview Ridges Hospital, Burnsville, Minnesota, United States

Mercy Hospital, Coon Rapids, Minnesota, United States

Essentia Health Cancer Center, Duluth, Minnesota, United States

Essentia Health Saint Mary's Medical Center, Duluth, Minnesota, United States

Miller-Dwan Hospital, Duluth, Minnesota, United States

Fairview Southdale Hospital, Edina, Minnesota, United States

Unity Hospital, Fridley, Minnesota, United States

Hutchinson Area Health Care, Hutchinson, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States

Saint John's Hospital - Healtheast, Maplewood, Minnesota, United States

Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States

Hennepin County Medical Center, Minneapolis, Minnesota, United States

Health Partners Inc, Minneapolis, Minnesota, United States

New Ulm Medical Center, New Ulm, Minnesota, United States

North Memorial Medical Health Center, Robbinsdale, Minnesota, United States

Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota, United States

Saint Cloud Hospital, Saint Cloud, Minnesota, United States

Metro Minnesota Community Oncology Research Consortium, Saint Louis Park, Minnesota, United States

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, United States

Regions Hospital, Saint Paul, Minnesota, United States

United Hospital, Saint Paul, Minnesota, United States

Saint Francis Regional Medical Center, Shakopee, Minnesota, United States

Lakeview Hospital, Stillwater, Minnesota, United States

Ridgeview Medical Center, Waconia, Minnesota, United States

Rice Memorial Hospital, Willmar, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States

Gulfport Memorial Hospital, Gulfport, Mississippi, United States

Hattiesburg Clinic - Hematology/Oncology Clinic, Hattiesburg, Mississippi, United States

Forrest General Hospital / Cancer Center, Hattiesburg, Mississippi, United States

University of Mississippi Medical Center, Jackson, Mississippi, United States

Singing River Hospital, Pascagoula, Mississippi, United States

Central Care Cancer Center - Bolivar, Bolivar, Missouri, United States

Parkland Health Center-Bonne Terre, Bonne Terre, Missouri, United States

Cox Cancer Center Branson, Branson, Missouri, United States

Southeast Missouri Hospital, Cape Girardeau, Missouri, United States

Saint Francis Medical Center, Cape Girardeau, Missouri, United States

Southeast Cancer Center, Cape Girardeau, Missouri, United States

Veterans Administration, Columbia, Missouri, United States

MU Health - University Hospital/Ellis Fischel Cancer Center, Columbia, Missouri, United States

Centerpoint Medical Center LLC, Independence, Missouri, United States

MU Health Care Goldschmidt Cancer Center, Jefferson City, Missouri, United States

Freeman Health System, Joplin, Missouri, United States

Mercy Hospital Joplin, Joplin, Missouri, United States

University Health Truman Medical Center, Kansas City, Missouri, United States

Saint Luke's Hospital of Kansas City, Kansas City, Missouri, United States

Saint Joseph Health Center, Kansas City, Missouri, United States

North Kansas City Hospital, Kansas City, Missouri, United States

Heartland Hematology and Oncology Associates Incorporated, Kansas City, Missouri, United States

Research Medical Center, Kansas City, Missouri, United States

Saint Luke's East - Lee's Summit, Lee's Summit, Missouri, United States

Liberty Radiation Oncology Center, Liberty, Missouri, United States

Delbert Day Cancer Institute at PCRMC, Rolla, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri, United States

Heartland Regional Medical Center, Saint Joseph, Missouri, United States

Saint Joseph Oncology Inc, Saint Joseph, Missouri, United States

SSM Health Saint Louis University Hospital, Saint Louis, Missouri, United States

Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States

Washington University School of Medicine, Saint Louis, Missouri, United States

Missouri Baptist Medical Center, Saint Louis, Missouri, United States

Center for Cancer Care and Research, Saint Louis, Missouri, United States

Comprehensive Cancer Care PC, Saint Louis, Missouri, United States

Mercy Hospital Saint Louis, Saint Louis, Missouri, United States

Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri, United States

Cancer Research for the Ozarks NCORP, Springfield, Missouri, United States

Mercy Hospital Springfield, Springfield, Missouri, United States

CoxHealth South Hospital, Springfield, Missouri, United States

Missouri Baptist Sullivan Hospital, Sullivan, Missouri, United States

BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri, United States

Billings Clinic Cancer Center, Billings, Montana, United States

Northern Rockies Radiation Oncology Center, Billings, Montana, United States

Saint Vincent Healthcare, Billings, Montana, United States

Montana Cancer Consortium NCORP, Billings, Montana, United States

Saint Vincent Frontier Cancer Center, Billings, Montana, United States

Bozeman Health Deaconess Hospital, Bozeman, Montana, United States

Saint James Community Hospital and Cancer Treatment Center, Butte, Montana, United States

Benefis Sletten Cancer Institute, Great Falls, Montana, United States

Berdeaux, Donald MD (UIA Investigator), Great Falls, Montana, United States

Great Falls Clinic, Great Falls, Montana, United States

Northern Montana Hospital, Havre, Montana, United States

Saint Peter's Community Hospital, Helena, Montana, United States

Glacier Oncology PLLC, Kalispell, Montana, United States

Kalispell Medical Oncology, Kalispell, Montana, United States

Kalispell Regional Medical Center, Kalispell, Montana, United States

Montana Cancer Specialists, Missoula, Montana, United States

Saint Patrick Hospital - Community Hospital, Missoula, Montana, United States

Community Medical Center, Missoula, Montana, United States

Guardian Oncology and Center for Wellness, Missoula, Montana, United States

Nebraska Cancer Specialists/Oncology Hematology West PC, Grand Island, Nebraska, United States

Heartland Hematology and Oncology, Kearney, Nebraska, United States

CHI Health Good Samaritan, Kearney, Nebraska, United States

Nebraska Hematology and Oncology, Lincoln, Nebraska, United States

Nebraska Cancer Research Center, Lincoln, Nebraska, United States

Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States

Cancer Partners of Nebraska, Lincoln, Nebraska, United States

Faith Regional Health Services Carson Cancer Center, Norfolk, Nebraska, United States

Great Plains Health Callahan Cancer Center, North Platte, Nebraska, United States

Missouri Valley Cancer Consortium, Omaha, Nebraska, United States

Nebraska Methodist Hospital, Omaha, Nebraska, United States

Alegent Health Immanuel Medical Center, Omaha, Nebraska, United States

Hematology and Oncology Consultants PC, Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States

Nebraska Cancer Specialists - Omaha, Omaha, Nebraska, United States

Alegent Health Lakeside Hospital, Omaha, Nebraska, United States

Oncology Hematology West PC, Omaha, Nebraska, United States

Urology Cancer Center PC, Omaha, Nebraska, United States

Creighton University Medical Center, Omaha, Nebraska, United States

University of Nebraska Medical Center, Omaha, Nebraska, United States

Midlands Community Hospital, Papillion, Nebraska, United States

Regional West Medical Center Cancer Center, Scottsbluff, Nebraska, United States

Cancer and Blood Specialists-Henderson, Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada, United States

Las Vegas Cancer Center-Henderson, Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Southeast Henderson, Henderson, Nevada, United States

GenesisCare USA - Henderson, Henderson, Nevada, United States

University Medical Center of Southern Nevada, Las Vegas, Nevada, United States

Cancer and Blood Specialists-Shadow, Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Central, Las Vegas, Nevada, United States

GenesisCare USA - Las Vegas, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-San Martin, Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Southeast, Las Vegas, Nevada, United States

Cancer Therapy and Integrative Medicine, Las Vegas, Nevada, United States

Cancer and Blood Specialists-Tenaya, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Northwest, Las Vegas, Nevada, United States

GenesisCare USA - Vegas Tenaya, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Tenaya, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada-Summerlin, Las Vegas, Nevada, United States

Summerlin Hospital Medical Center, Las Vegas, Nevada, United States

Las Vegas Cancer Center-Medical Center, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States

GenesisCare USA - Fort Apache, Las Vegas, Nevada, United States

OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada, United States

Nevada Cancer Research Foundation NCORP, Las Vegas, Nevada, United States

Renown Regional Medical Center, Reno, Nevada, United States

Cooper Hospital University Medical Center, Camden, New Jersey, United States

Veterans Adminstration New Jersey Health Care System, East Orange, New Jersey, United States

Hackensack University Medical Center, Hackensack, New Jersey, United States

Morristown Medical Center, Morristown, New Jersey, United States

Inspira Medical Center Mullica Hill, Mullica Hill, New Jersey, United States

Rutgers New Jersey Medical School, Newark, New Jersey, United States

Newark Beth Israel Medical Center, Newark, New Jersey, United States

Overlook Hospital, Summit, New Jersey, United States

Inspira Medical Center Vineland, Vineland, New Jersey, United States

Lovelace Medical Center-Saint Joseph Square, Albuquerque, New Mexico, United States

University of New Mexico Cancer Center, Albuquerque, New Mexico, United States

Memorial Medical Center - Las Cruces, Las Cruces, New Mexico, United States

Hematology Oncology Associates of Central New York-Auburn, Auburn, New York, United States

Montefiore Medical Center-Weiler Hospital, Bronx, New York, United States

Montefiore Medical Center - Moses Campus, Bronx, New York, United States

Kings County Hospital, Brooklyn, New York, United States

State University of New York Downstate Medical Center, Brooklyn, New York, United States

Veteran Affairs New York Harbor Healthcare System-Brooklyn Campus, Brooklyn, New York, United States

Veterans Affairs Western New York Health Care System-Buffalo, Buffalo, New York, United States

Mary Imogene Bassett Hospital, Cooperstown, New York, United States

Hematology Oncology Associates of Central New York-East Syracuse, East Syracuse, New York, United States

Glens Falls Hospital, Glens Falls, New York, United States

Garnet Health Medical Center, Middletown, New York, United States

Mount Sinai Union Square, New York, New York, United States

NYP/Weill Cornell Medical Center, New York, New York, United States

Hematology Oncology Associates of Central New York-Onondaga Hill, Syracuse, New York, United States

Faxton-Saint Luke's Healthcare, Utica, New York, United States

Novant Health Presbyterian Medical Center, Charlotte, North Carolina, United States

Novant Health Carolina Surgical - Randolph, Charlotte, North Carolina, United States

Oncology Specialists of Charlotte, Charlotte, North Carolina, United States

Southern Oncology Specialists-Charlotte, Charlotte, North Carolina, United States

Southeastern Medical Oncology Center-Clinton, Clinton, North Carolina, United States

Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina, United States

Wayne Memorial Hospital, Goldsboro, North Carolina, United States

Novant Health Cancer Institute - Huntersville, Huntersville, North Carolina, United States

Southern Oncology Specialists-Huntersville, Huntersville, North Carolina, United States

Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina, United States

ECU Health Oncology Kinston, Kinston, North Carolina, United States

Matthews Radiation Oncology Center, Matthews, North Carolina, United States

Novant Health Cancer Institute - Matthews, Matthews, North Carolina, United States

Novant Health Cancer Institute - Mooresville, Mooresville, North Carolina, United States

Mid Dakota Clinic, Bismarck, North Dakota, United States

Saint Alexius Medical Center, Bismarck, North Dakota, United States

Sanford Bismarck Medical Center, Bismarck, North Dakota, United States

Altru Cancer Center, Grand Forks, North Dakota, United States

Trinity Cancer Care Center, Minot, North Dakota, United States

Summa Health System - Akron Campus, Akron, Ohio, United States

Cleveland Clinic Akron General, Akron, Ohio, United States

Summa Health System - Barberton Campus, Barberton, Ohio, United States

UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio, United States

Mary Rutan Hospital, Bellefontaine, Ohio, United States

Strecker Cancer Center-Belpre, Belpre, Ohio, United States

Cleveland Clinic Mercy Hospital, Canton, Ohio, United States

Aultman Health Foundation, Canton, Ohio, United States

Adena Regional Medical Center, Chillicothe, Ohio, United States

University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio, United States

Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio, United States

Bethesda North Hospital, Cincinnati, Ohio, United States

TriHealth Cancer Institute-Westside, Cincinnati, Ohio, United States

TriHealth Cancer Institute-Anderson, Cincinnati, Ohio, United States

Case Western Reserve University, Cleveland, Ohio, United States

MetroHealth Medical Center, Cleveland, Ohio, United States

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

Columbus Oncology and Hematology Associates Inc, Columbus, Ohio, United States

Riverside Methodist Hospital, Columbus, Ohio, United States

Columbus NCI Community Oncology Research Program, Columbus, Ohio, United States

Grant Medical Center, Columbus, Ohio, United States

The Mark H Zangmeister Center, Columbus, Ohio, United States

Mount Carmel Health Center West, Columbus, Ohio, United States

Doctors Hospital, Columbus, Ohio, United States

Miami Valley Hospital North, Dayton, Ohio, United States

Dayton Veterans Affairs Medical Center, Dayton, Ohio, United States

Delaware Health Center-Grady Cancer Center, Delaware, Ohio, United States

Delaware Radiation Oncology, Delaware, Ohio, United States

Grady Memorial Hospital, Delaware, Ohio, United States

Wayne Hospital, Greenville, Ohio, United States

Fairfield Medical Center, Lancaster, Ohio, United States

Lancaster Radiation Oncology, Lancaster, Ohio, United States

Saint Rita's Medical Center, Lima, Ohio, United States

Marietta Memorial Hospital, Marietta, Ohio, United States

UH Seidman Cancer Center at Landerbrook Health Center, Mayfield Heights, Ohio, United States

UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio, United States

Knox Community Hospital, Mount Vernon, Ohio, United States

Licking Memorial Hospital, Newark, Ohio, United States

Newark Radiation Oncology, Newark, Ohio, United States

Southern Ohio Medical Center, Portsmouth, Ohio, United States

UH Seidman Cancer Center at Firelands Regional Medical Center, Sandusky, Ohio, United States

Springfield Regional Medical Center, Springfield, Ohio, United States

Upper Valley Medical Center, Troy, Ohio, United States

Saint Ann's Hospital, Westerville, Ohio, United States

UHHS-Westlake Medical Center, Westlake, Ohio, United States

Genesis Healthcare System Cancer Care Center, Zanesville, Ohio, United States

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

Integris Southwest Medical Center, Oklahoma City, Oklahoma, United States

Cancer Care Associates, Oklahoma City, Oklahoma, United States

Integris Cancer Institute of Oklahoma, Oklahoma City, Oklahoma, United States

Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma, United States

Salem Hospital, Salem, Oregon, United States

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania, United States

UPMC-Heritage Valley Health System Beaver, Beaver, Pennsylvania, United States

Saint Luke's University Hospital-Bethlehem Campus, Bethlehem, Pennsylvania, United States

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania, United States

Geisinger Medical Center, Danville, Pennsylvania, United States

Delaware County Memorial Hospital, Drexel Hill, Pennsylvania, United States

Pocono Medical Center, East Stroudsburg, Pennsylvania, United States

UPMC Cancer Centers - Arnold Palmer Pavilion, Greensburg, Pennsylvania, United States

Geisinger Medical Center-Cancer Center Hazleton, Hazleton, Pennsylvania, United States

UPMC-Johnstown/John P. Murtha Regional Cancer Center, Johnstown, Pennsylvania, United States

Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania, United States

Lewistown Hospital, Lewistown, Pennsylvania, United States

UPMC Cancer Center at UPMC McKeesport, McKeesport, Pennsylvania, United States

Riddle Memorial Hospital, Media, Pennsylvania, United States

UPMC Hillman Cancer Center in Coraopolis, Moon, Pennsylvania, United States

University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania, United States

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

Temple University Hospital, Philadelphia, Pennsylvania, United States

Allegheny General Hospital, Pittsburgh, Pennsylvania, United States

UPMC-Magee Womens Hospital, Pittsburgh, Pennsylvania, United States

UPMC-Presbyterian Hospital, Pittsburgh, Pennsylvania, United States

UPMC-Saint Margaret, Pittsburgh, Pennsylvania, United States

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania, United States

UPMC-Shadyside Hospital, Pittsburgh, Pennsylvania, United States

UPMC Jefferson Regional Radiation Oncology, Pittsburgh, Pennsylvania, United States

UPMC-Passavant Hospital, Pittsburgh, Pennsylvania, United States

VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, United States

UPMC-Saint Clair Hospital Cancer Center, Pittsburgh, Pennsylvania, United States

Geisinger Cancer Services-Pottsville, Pottsville, Pennsylvania, United States

Penn State Health Saint Joseph Medical Center, Reading, Pennsylvania, United States

Guthrie Medical Group PC-Robert Packer Hospital, Sayre, Pennsylvania, United States

Mercy Hospital, Scranton, Pennsylvania, United States

Hematology and Oncology Associates of North East Pennsylvania, Scranton, Pennsylvania, United States

Scranton Hematology Oncology, Scranton, Pennsylvania, United States

UPMC Cancer Center at UPMC Northwest, Seneca, Pennsylvania, United States

Geisinger Medical Group, State College, Pennsylvania, United States

UPMC Uniontown Hospital Radiation Oncology, Uniontown, Pennsylvania, United States

Associates In Hematology Oncology PC-Upland, Upland, Pennsylvania, United States

UPMC Washington Hospital Radiation Oncology, Washington, Pennsylvania, United States

Chester County Hospital, West Chester, Pennsylvania, United States

Reading Hospital, West Reading, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania, United States

UPMC Susquehanna, Williamsport, Pennsylvania, United States

Memorial Hospital of Rhode Island, Pawtucket, Rhode Island, United States

Roger Williams Medical Center, Providence, Rhode Island, United States

Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina, United States

Prisma Health Cancer Institute - Easley, Easley, South Carolina, United States

McLeod Regional Medical Center, Florence, South Carolina, United States

Greenville Health System Cancer Institute-Andrews, Greenville, South Carolina, United States

Prisma Health Cancer Institute - Butternut, Greenville, South Carolina, United States

Prisma Health Cancer Institute - Faris, Greenville, South Carolina, United States

Prisma Health Greenville Memorial Hospital, Greenville, South Carolina, United States

Self Regional Healthcare, Greenwood, South Carolina, United States

Prisma Health Cancer Institute - Greer, Greer, South Carolina, United States

Prisma Health Cancer Institute - Seneca, Seneca, South Carolina, United States

Rapid City Regional Hospital, Rapid City, South Dakota, United States

Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota, United States

Avera Cancer Institute, Sioux Falls, South Dakota, United States

Medical X-Ray Center, Sioux Falls, South Dakota, United States

Avera McKennan Hospital and University Health Center, Sioux Falls, South Dakota, United States

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota, United States

Erlanger Medical Center, Chattanooga, Tennessee, United States

Memorial Hospital, Chattanooga, Tennessee, United States

Vanderbilt-Ingram Cancer Center Cool Springs, Franklin, Tennessee, United States

Pulmonary Medicine Center of Chattanooga-Hixson, Hixson, Tennessee, United States

University of Tennessee - Knoxville, Knoxville, Tennessee, United States

Nashville Oncology Associates PC, Nashville, Tennessee, United States

Meharry Medical College, Nashville, Tennessee, United States

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

Memorial GYN Plus, Ooltewah, Tennessee, United States

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas, United States

Baylor Saint Luke's Medical Center, Houston, Texas, United States

Ben Taub General Hospital, Houston, Texas, United States

Houston Methodist Hospital, Houston, Texas, United States

Michael E DeBakey VA Medical Center, Houston, Texas, United States

Texas Tech University Health Sciences Center-Lubbock, Lubbock, Texas, United States

Audie L Murphy VA Hospital, San Antonio, Texas, United States

Cancer Therapy and Research Center at The UT Health Science Center at San Antonio, San Antonio, Texas, United States

University Hospital, San Antonio, Texas, United States

University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

American Fork Hospital / Huntsman Intermountain Cancer Center, American Fork, Utah, United States

Sandra L Maxwell Cancer Center, Cedar City, Utah, United States

Logan Regional Hospital, Logan, Utah, United States

Intermountain Medical Center, Murray, Utah, United States

McKay-Dee Hospital Center, Ogden, Utah, United States

Utah Valley Regional Medical Center, Provo, Utah, United States

Saint George Regional Medical Center, Saint George, Utah, United States

Utah Cancer Specialists-Salt Lake City, Salt Lake City, Utah, United States

LDS Hospital, Salt Lake City, Utah, United States

Danville Regional Medical Center, Danville, Virginia, United States

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia, United States

PeaceHealth Saint Joseph Medical Center, Bellingham, Washington, United States

Highline Medical Center-Main Campus, Burien, Washington, United States

Saint Elizabeth Hospital, Enumclaw, Washington, United States

Saint Francis Hospital, Federal Way, Washington, United States

Swedish Cancer Institute-Issaquah, Issaquah, Washington, United States

EvergreenHealth Medical Center, Kirkland, Washington, United States

Saint Clare Hospital, Lakewood, Washington, United States

Olympic Medical Center, Port Angeles, Washington, United States

Southlake Clinic, Renton, Washington, United States

Valley Medical Center, Renton, Washington, United States

Virginia Mason Medical Center, Seattle, Washington, United States

Pacific Medical Center-First Hill, Seattle, Washington, United States

Swedish Medical Center-First Hill, Seattle, Washington, United States

Franciscan Research Center-Northwest Medical Plaza, Tacoma, Washington, United States

Northwest Medical Specialties PLLC, Tacoma, Washington, United States

West Virginia University Charleston Division, Charleston, West Virginia, United States

Edwards Comprehensive Cancer Center, Huntington, West Virginia, United States

West Virginia University Healthcare, Morgantown, West Virginia, United States

Camden Clark Medical Center, Parkersburg, West Virginia, United States

Langlade Hospital and Cancer Center, Antigo, Wisconsin, United States

Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin, United States

Marshfield Clinic-Chippewa Center, Chippewa Falls, Wisconsin, United States

HSHS Sacred Heart Hospital, Eau Claire, Wisconsin, United States

Marshfield Clinic Cancer Center at Sacred Heart, Eau Claire, Wisconsin, United States

Aurora Health Center-Fond du Lac, Fond Du Lac, Wisconsin, United States

Green Bay Oncology at Saint Vincent Hospital, Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin, United States

Green Bay Oncology Limited at Saint Mary's Hospital, Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin, United States

Aurora BayCare Medical Center, Green Bay, Wisconsin, United States

University of Wisconsin Carbone Cancer Center Johnson Creek, Johnson Creek, Wisconsin, United States

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin, United States

Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin, United States

Holy Family Memorial Hospital, Manitowoc, Wisconsin, United States

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin, United States

Bay Area Medical Center, Marinette, Wisconsin, United States

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin, United States

Marshfield Medical Center, Marshfield, Wisconsin, United States

Ascension Columbia Saint Mary's Hospital Ozaukee, Mequon, Wisconsin, United States

Ascension Columbia Saint Mary's Hospital - Milwaukee, Milwaukee, Wisconsin, United States

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin, United States

Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin, United States

Cancer Center of Western Wisconsin, New Richmond, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Oconto Falls, Oconto Falls, Wisconsin, United States

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin, United States

Ascension All Saints Hospital, Racine, Wisconsin, United States

Aurora Cancer Care-Racine, Racine, Wisconsin, United States

Ascension Saint Mary's Hospital, Rhinelander, Wisconsin, United States

Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin, United States

HSHS Saint Nicholas Hospital, Sheboygan, Wisconsin, United States

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin, United States

Ascension Saint Michael's Hospital, Stevens Point, Wisconsin, United States

Green Bay Oncology - Sturgeon Bay, Sturgeon Bay, Wisconsin, United States

Aurora Medical Center in Summit, Summit, Wisconsin, United States

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin, United States

Aurora Cancer Care-Waukesha, Waukesha, Wisconsin, United States

Aspirus Regional Cancer Center, Wausau, Wisconsin, United States

Marshfield Medical Center - Weston, Weston, Wisconsin, United States

Aspirus Cancer Care - Wisconsin Rapids, Wisconsin Rapids, Wisconsin, United States

Marshfield Clinic - Wisconsin Rapids Center, Wisconsin Rapids, Wisconsin, United States

Rocky Mountain Oncology, Casper, Wyoming, United States

Cheyenne Regional Medical Center-West, Cheyenne, Wyoming, United States

Welch Cancer Center, Sheridan, Wyoming, United States

San Juan City Hospital, San Juan, , Puerto Rico

University Of Pretoria, Pretoria, , South Africa

Contact Details

Name: Athanassios (Ethan) Argiris

Affiliation: ECOG-ACRIN Cancer Research Group

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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