Spots Global Cancer Trial Database for DS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing Gastric Cancer [DESTINY-Gastric01]
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Trial Identification
Brief Title: DS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing Gastric Cancer [DESTINY-Gastric01]
Official Title: A Phase 2, Multicenter, Open-label Study of DS-8201a in Subjects With HER2-expressing Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Study ID: NCT03329690
Conditions
Study Description
Brief Summary: The primary purpose of this trial is to compare the efficacy and safety of DS-8201a and physician's choice treatment in HER2-overexpressing advanced gastric or gastroesophageal junction adenocarcinoma patients who have progressed on two prior treatment regimens including fluoropyrimidine agent, platinum agent, and trastuzumab.
Detailed Description:
Eligibility
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Aichi Cancer Center Hospital, Nagoya, Aichi, Japan
Hirosaki University Hospital, Hirosaki, Aomori, Japan
National Cancer Center Hospital East, Kashiwa, Chiba, Japan
National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime, Japan
Japan Community Health Care Organization Kyushu Hospital, Kitakyushu, Fukuoka, Japan
Gunma Prefectural Cancer Center, Ōta, Gunma, Japan
Kure Medical Center, Kure, Hiroshima, Japan
Hokkaido University Hospital, Sapporo, Hokkaido, Japan
Hyogo Cancer Center, Akashi, Hyogo, Japan
Kansai Rosai Hospital, Amagasaki, Hyogo, Japan
Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan
Ibaraki Prefectural Central Hospital, Kasama, Ibaraki, Japan
Kanazawa University Hospital, Kanazawa, Ishikawa, Japan
Iwate Medical University Hospital, Shiwa-gun, Iwate, Japan
Kagawa University Hospital, Kita, Kagawa, Japan
St. Marianna University School of Medicine Hospital, Kawasaki, Kanagawa, Japan
The Kitasato Institute Kitasato University Hospital, Sagamihara, Kanagawa, Japan
Yokohama City University Medical Center, Yokohama, Kanagawa, Japan
Kanagawa Cancer Center, Yokohama, Kanagawa, Japan
Japanese Red Cross Kyoto Daini Hospital, Kamigyō-ku, Kyoto, Japan
Miyagi Cancer Center, Natori, Miyagi, Japan
Osaki Citizen Hospital, Osaki, Miyagi, Japan
Osaka University Hospital, Suita, Osaka, Japan
Toyonaka Municipal Hospital, Toyonaka, Osaka, Japan
Tochigi Cancer Center, Utsunomiya, Tochigi, Japan
Tokyo Metropolitan Komagome Hospital, Bunkyō-Ku, Tokyo, Japan
National Cancer Center Hospital, Chuo Ku, Tokyo, Japan
The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto-Ku, Tokyo, Japan
Showa University Koto Toyosu Hospital, Koto-Ku, Tokyo, Japan
Toranomon Hospital, Minato-Ku, Tokyo, Japan
Chiba Cancer Center, Chiba, , Japan
Fukui Prefectural Hospital, Fukui, , Japan
National Hospital Organization Kyushu Cancer Center, Fukuoka, , Japan
Kyushu University Hospital, Fukuoka, , Japan
Gifu University Hospital, Gifu, , Japan
Hiroshima City Asa Citizens Hospital, Hiroshima, , Japan
Hiroshima Prefectural Hospital, Hiroshima, , Japan
Kochi Health Sciences Center, Kochi, , Japan
Niigata Cancer Center Hospital, Niigata, , Japan
Okayama University Hospital, Okayama, , Japan
Local Incorporated Administrative Agency Osaka City Hospital Organization Osaka City General Hospital, Osaka, , Japan
Osaka International Cancer Institute, Osaka, , Japan
Osaka General Medical Center, Osaka, , Japan
Kindai University Hospital, Osaka, , Japan
Saitama Cancer Center, Saitama, , Japan
Shizuoka Cancer Center, Shizuoka, , Japan
Shizuoka General Hospital, Shizuoka, , Japan
Keio University Hospital, Tokyo, , Japan
Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do, Korea, Republic of
National Cancer Center, Ilsan, Gyeonggi-do, Korea, Republic of
Inje University Haeundae Paik Hospital, Busan, , Korea, Republic of
Dong-A University Hospital, Busan, , Korea, Republic of
Kyungpook National University Chilgok Hospital, Daegu, , Korea, Republic of
Chonnam National University Hwasun Hospital, Gwangju, , Korea, Republic of
Gachon University Gil Medical Center, Incheon, , Korea, Republic of
Chonbuk National University Hospital, Jeonju, , Korea, Republic of
Seoul National University Bundang Hospital, Seongnam, , Korea, Republic of
Korea University Anam Hospital, Seoul, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Yonsei Cancer Center, Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Gangnam Severance Hospital, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, , Korea, Republic of
Chung-Ang University Hospital, Seoul, , Korea, Republic of
Korea University Guro Hospital, Seoul, , Korea, Republic of
Contact Details
Name: Global Clinical Leader
Affiliation: Daiichi Sankyo
Role: STUDY_DIRECTOR
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