Spots Global Cancer Trial Database for A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors
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Trial Identification
Brief Title: A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors
Official Title: A Dose-Escalation and Expansion Study of the Safety and Pharmacokinetics of XL092 as Single-Agent and Combination Therapy in Subjects With Inoperable Locally Advanced or Metastatic Solid Tumors
Study ID: NCT03845166
Study Description
Brief Summary: This is a Phase 1, open-label, dose-escalation and expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity, and effect on biomarkers of XL092 administered alone, in combination with atezolizumab, and in combination with avelumab to subjects with advanced solid tumors.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Exelixis Clinical Site #6, Duarte, California, United States
Exelixis Clinical Site #49, La Jolla, California, United States
Exelixis Clinical Site #7, Los Angeles, California, United States
Exelixis Clinical #71, Palo Alto, California, United States
Exelixis Clinical Site #66, San Francisco, California, United States
Exelixis Clinical Site #15, Lake Mary, Florida, United States
Exelixis Clinical Site #24, Miami, Florida, United States
Exelixis Clinical Site #11, Atlanta, Georgia, United States
Exelixis Clinical Site #80, Atlanta, Georgia, United States
Exelixis Clinical Site #41, Iowa City, Iowa, United States
Exelixis Clinical Site #36, Westwood, Kansas, United States
Exelixis Clinical Site #62, Scarborough, Maine, United States
Exelixis Clinical Site #44, Baltimore, Maryland, United States
Exelixis Clinical Site #4, Boston, Massachusetts, United States
Exelixis Clinical Site #45, Ann Arbor, Michigan, United States
Exelixis Clinical Site #2, Grand Rapids, Michigan, United States
Exelixis Clinical Site #25, Saint Paul, Minnesota, United States
Exelixis Clinical Site #13, Omaha, Nebraska, United States
Exelixis Clinical Site #9, East Brunswick, New Jersey, United States
Exelixis Clinical Site #83, New Brunswick, New Jersey, United States
Exelixis Clinical Site #35, New York, New York, United States
Exelixis Clinical #78, New York, New York, United States
Exelixis Clinical #74, Cincinnati, Ohio, United States
Exelixis Clinical Site #60, Cleveland, Ohio, United States
Exelixis Clinical Site #59, Hershey, Pennsylvania, United States
Exelixis Clinical Site #58, Philadelphia, Pennsylvania, United States
Exelixis Clinical Site #12, Pittsburgh, Pennsylvania, United States
Exelixis Clinical Site #61, Charleston, South Carolina, United States
Exelixis Clinical Site #50, Myrtle Beach, South Carolina, United States
Exelixis Clinical Site #33, Germantown, Tennessee, United States
Exelixis Clinical Site #3, Houston, Texas, United States
Exelixis Clinical Site #1, San Antonio, Texas, United States
Exelixis Clinical Site #5, Salt Lake City, Utah, United States
Exelixis Clinical Site #8, Charlottesville, Virginia, United States
Exelixis Clinical Site #43, Richmond, Virginia, United States
Exelixis Clinical Site #26, Spokane, Washington, United States
Exelixis Clinical Site #52, Darlinghurst, New South Wales, Australia
Exelixis Clinical Site #53, Liverpool, New South Wales, Australia
Exelixis Clinical #75, South Brisbane, Queensland, Australia
Exelixis Clinical Site #56, Kurralta Park, South Australia, Australia
Exelixis Clinical Site #63, Heidelberg, Victoria, Australia
Exelixis Clinical Site #44, Edegem, Antwerpen, Belgium
Exelixis Clinical Site #51, Bruxelles, Brussels, Belgium
Exelixis Clinical Site #65, Gent, Oost-Vlaanderen, Belgium
Exelixis Clinical Site #21, Brno, , Czechia
Exelixis Clinical Site #42, Hradec Králové, , Czechia
Exelixis Clinical Site #10, Olomouc, , Czechia
Exelixis Clinical Site #27, Praha, , Czechia
Exelixis Clinical Site #46, Clermont, Ferrand, France
Exelixis Clinical Site #37, Saint-Herblain Cedex, Loire Atlantique, France
Exelixis Clinical #72, Bordeaux, , France
Exelixis Clinical Site #32, Caen Cedex 5, , France
Exelixis Clinical Site #48, Marseille, , France
Exelixis Clinical Site #14, Paris, , France
Exelixis Clinical Site #39, Pierre-Bénite, , France
Exelixis Clinical Site #47, Poitiers, , France
Exelixis Clinical Site #22, Suresnes, , France
Exelixis Clinical Site #57, Toulouse Cedex 9, , France
Exelixis Clinical #77, Villejuif, , France
Exelixis Clinical Site #38, Nürtingen, Baden-Wuerttemberg, Germany
Exelixis Clinical Site #28, München, Bavaria, Germany
Exelixis Clinical Site #31, Münster, North Rhine-Westphalia, Germany
Exelixis Clinical Site #64, Hamburg, , Germany
Exelixis Clinical Site #67, Milano, MI, Italy
Exelixis Clinical Site #69, Pavia, PV, Italy
Exelixis Clinical Site #54, Milan, , Italy
Exelixis Clinical #73, Napoli, , Italy
Exelixis Clinical Site #79, Amsterdam, Noord-Holland, Netherlands
Exelixis Clinical Site #82, Amsterdam, North Holland, Netherlands
Exelixis Clinical #76, Rotterdam, South Holland, Netherlands
Exelixis Clinical Site #23, Sabadell, Barcelona, Spain
Exelixis Clinical Site #20, Santiago De Compostela, La Coruna, Spain
Exelixis Clinical Site #18, Barcelona, , Spain
Exelixis Clinical Site #19, Barcelona, , Spain
Exelixis Clinical Site #29, Barcelona, , Spain
Exelixis Clinical Site #30, Barcelona, , Spain
Exelixis Clinical Site #81, Madrid, , Spain
Exelixis Clinical Site #34, Madrid, , Spain
Exelixis Clinical Site #55, Madrid, , Spain
Exelixis Clinical Site #17, Madrid, , Spain
Exelixis Clinical Site #16, Sevilla, , Spain
Exelixis Clinical #70, London, England, United Kingdom
Exelixis Clinical Site #40, Sutton, England, United Kingdom
Exelixis Clinical Site #68, Preston, Lancashire, United Kingdom
Contact Details
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