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Brief Title: Oxaliplatin and Cetuximab in First-line Treatment of Metastatic Colorectal Cancer (mCRC)
Official Title: Open, Randomized, Controlled, Multicenter Phase II Study Comparing 5-FU/FA Plus Oxaliplatin (FOLFOX-4) Plus Cetuximab Versus 5-FU/FA Plus Oxaliplatin (FOLFOX-4) as First-line Treatment for Epidermal Growth Factor Receptor-expressing Metastatic Colorectal Cancer
Study ID: NCT00125034
Brief Summary: This is an open label, randomized, controlled, multicenter phase II study comparing 5-FU/FA + oxaliplatin (FOLFOX-4) + cetuximab versus 5-FU/FA + oxaliplatin as first-line treatment for epidermal growth factor receptor (EGFR)-expressing mCRC.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Graz, , Austria
Research Site, Linz, , Austria
Research Site, Salzburg, , Austria
Research Site, Wien, , Austria
Research Site, Zams, , Austria
Research Site, Antwerpen, , Belgium
Research Site, Bonheiden, , Belgium
Research Site, Brugge, , Belgium
Research Site, Hasselt, , Belgium
Research Site, Leuven, , Belgium
Research Site, Roeselare, , Belgium
Research Site, Turnhout, , Belgium
Research Site, ZU Gent, , Belgium
Research Site, Besancon, , France
Research Site, Clermond Ferrand, , France
Research Site, Clichy, , France
Research Site, Montpellier, , France
Research Site, Paris, , France
Research Site, Rouen, , France
Research Site, Strasbourg, , France
Research Site, Aschaffenburg, , Germany
Research Site, Dresden, , Germany
Research Site, Essen, , Germany
Research Site, Hamburg, , Germany
Research Site, Kiel, , Germany
Research Site, Magdeburg, , Germany
Research Site, Mannheim, , Germany
Research Site, Nürnberg, , Germany
Research Site, Tübingen, , Germany
Research Site, Athens, , Greece
Research Site, Loannina, , Greece
Research Site, Thessaloniki, , Greece
Research Site, Haifa, , Israel
Research Site, Kfar-Saba, , Israel
Research Site, Petah Tiqva, , Israel
Research Site, Rehovot, , Israel
Research Site, Tel-Aviv, , Israel
Research Site, Tel-Hashomer, , Israel
Research Site, Brescia, , Italy
Research Site, Milano, , Italy
Research Site, Padova, , Italy
Research Site, Pavia, , Italy
Research Site, Rome, , Italy
Research Site, Torino, , Italy
Research Site, Bialystok, , Poland
Research Site, Krakow, , Poland
Research Site, Lublin, , Poland
Research Site, Opole, , Poland
Research Site, Poznan, , Poland
Research Site, Szczecin, , Poland
Research Site, Warszawa, , Poland
Research Site, Lisbon, , Portugal
Research Site, Santa Maira da Feira, , Portugal
Research Site, Alba Iulia, , Romania
Research Site, Bucurest, , Romania
Research Site, Onesti, , Romania
Research Site, Oradea, , Romania
Research Site, Timisoara, , Romania
Research Site, Kazan, , Russian Federation
Research Site, Krasnodar, , Russian Federation
Research Site, Moscow, , Russian Federation
Research Site, Obninsk, , Russian Federation
Research Site, Samara, , Russian Federation
Research Site, St. Petersburg, , Russian Federation
Research Site, Bilbao, , Spain
Research Site, Burgos, , Spain
Research Site, Girona, , Spain
Research Site, Madrid, , Spain
Research Site, Malaga, , Spain
Research Site, Orense, , Spain
Research Site, Reus, , Spain
Research Site, Valencia, , Spain
Research Site, Dnepropetrovsk, , Ukraine
Research Site, Kharkov, , Ukraine
Research Site, Kiev, , Ukraine
Research Site, Lviv, , Ukraine
Research Site, Simferopol, , Ukraine
Research Site, Vinnitsa, , Ukraine
Name: Bokemeyer, Prof. Dr.
Affiliation: Klinik für Onkologie, Hämatologie und Knochenmarktransplantationen Universitätsklinikum Hamburg-Eppendorf, Germany
Role: PRINCIPAL_INVESTIGATOR