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Brief Title: Study to Assess Safety & Tolerability of AZD2281 in Combination With Bevacizumab in Patients With Advanced Solid Tumours
Official Title: A Phase I, Open Label, Dual Centre Study To Assess The Safety And Tolerability Of AZD2281 In Combination With Bevacizumab (Avastin®) In Patients With Advanced Solid Tumours
Study ID: NCT00710268
Brief Summary: Phase I, open label, dual centre, dose finding study to evaluate the safety and tolerability of continuous twice daily oral dosing with AZD2281 when administered in combination with Bevacizumab 10mg/kg given every 2 weeks to patients with advanced solid tumours.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Manchester, , United Kingdom
Research Site, Oxford, , United Kingdom
Name: James Carmichael, BSc MBChB MD FRCP
Affiliation: KuDOS Pharmaceuticals Ltd
Role: STUDY_DIRECTOR
Name: Malcolm Ranson
Affiliation: Christie Hospital, Manchester, UK
Role: PRINCIPAL_INVESTIGATOR