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Spots Global Cancer Trial Database for Study to Assess Safety & Tolerability of AZD2281 in Combination With Bevacizumab in Patients With Advanced Solid Tumours

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Trial Identification

Brief Title: Study to Assess Safety & Tolerability of AZD2281 in Combination With Bevacizumab in Patients With Advanced Solid Tumours

Official Title: A Phase I, Open Label, Dual Centre Study To Assess The Safety And Tolerability Of AZD2281 In Combination With Bevacizumab (Avastin®) In Patients With Advanced Solid Tumours

Study ID: NCT00710268

Interventions

AZD2281
Bevacizumab

Study Description

Brief Summary: Phase I, open label, dual centre, dose finding study to evaluate the safety and tolerability of continuous twice daily oral dosing with AZD2281 when administered in combination with Bevacizumab 10mg/kg given every 2 weeks to patients with advanced solid tumours.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Research Site, Manchester, , United Kingdom

Research Site, Oxford, , United Kingdom

Contact Details

Name: James Carmichael, BSc MBChB MD FRCP

Affiliation: KuDOS Pharmaceuticals Ltd

Role: STUDY_DIRECTOR

Name: Malcolm Ranson

Affiliation: Christie Hospital, Manchester, UK

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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