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Brief Title: Safety Study of Increasing Doses of Combretasatin A1 Diphosphate (OXi4503) as Monotherapy in Subjects With Hepatic Tumor Burden
Official Title: A Multicenter, Open-label Phase 1b/2 Study to Assess the Safety and Clinical Activity of Intravenous Combretastatin A1 Diphosphate (OXi4503) as Monotherapy in Subjects With Primary or Secondary Hepatic Tumor Burden
Study ID: NCT00960557
Brief Summary: The purpose of this study is to determine the safety and tolerability of OXi4503 in subjects with relapsed or refractory carcinomas with hepatic tumor burden.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
OXiGENE Investigational Site, Westmead, New South Wales, Australia
OXiGENE Investigational Site, South Brisbane, Queensland, Australia
OXiGENE Investigational Site, Adelaide, South Australia, Australia
OXiGENE Investigational Site, Bentleigh, Victoria, Australia
Name: Michael Brown, MD
Affiliation: Royal Adelaide Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Jason Lickliter, MD
Affiliation: Monash Medical Centre
Role: PRINCIPAL_INVESTIGATOR
Name: Paul Mainwaring, MD
Affiliation: Mater Adult Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Michael Millward, MD
Affiliation: Sir Charles Gairdner Hospital
Role: PRINCIPAL_INVESTIGATOR