Spots Global Cancer Trial Database for Pazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Inflammatory Breast Cancer
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Trial Identification
Brief Title: Pazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Inflammatory Breast Cancer
Official Title: A Randomized, Multicenter, Phase III Study Comparing the Combination of Pazopanib and Lapatinib Versus Lapatinib Monotherapy in Patients With ErbB2 Over-expressing Inflammatory Breast Cancer
Study ID: NCT00558103
Conditions
Study Description
Brief Summary: The double blind part of the study is being conducted to compare the efficacy and safety of pazopanib in combination with lapatinib with that of lapatinib alone in subjects with inflammatory breast cancer whose tumors overexpress the ErbB2 protein. There is also an Open-label pazopanib arm to this study designed to test whether pazopanib given alone and lapatinib given alone would be safe and effective to treat patients with inflammatory breast cancer.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
GSK Investigational Site, Long Beach, California, United States
GSK Investigational Site, Sacramento, California, United States
GSK Investigational Site, Denver, Colorado, United States
GSK Investigational Site, Washington, District of Columbia, United States
GSK Investigational Site, Chicago, Illinois, United States
GSK Investigational Site, Zion, Illinois, United States
GSK Investigational Site, Scarborough, Maine, United States
GSK Investigational Site, Detroit, Michigan, United States
GSK Investigational Site, Omaha, Nebraska, United States
GSK Investigational Site, Voorhees, New Jersey, United States
GSK Investigational Site, Durham, North Carolina, United States
GSK Investigational Site, Philadelphia, Pennsylvania, United States
GSK Investigational Site, Charleston, South Carolina, United States
GSK Investigational Site, Memphis, Tennessee, United States
GSK Investigational Site, Houston, Texas, United States
GSK Investigational Site, Ogden, Utah, United States
GSK Investigational Site, Seattle, Washington, United States
GSK Investigational Site, Perth, Western Australia, Australia
GSK Investigational Site, Bruxelles, , Belgium
GSK Investigational Site, Edegem, , Belgium
GSK Investigational Site, Jette, , Belgium
GSK Investigational Site, Wilrijk, , Belgium
GSK Investigational Site, Montreal, Quebec, Canada
GSK Investigational Site, Montreal, Quebec, Canada
GSK Investigational Site, Temuco, Región De La Araucania, Chile
GSK Investigational Site, Santiago, Región Metro De Santiago, Chile
GSK Investigational Site, Viña del Mar, Valparaíso, Chile
GSK Investigational Site, Beijing, , China
GSK Investigational Site, Beijing, , China
GSK Investigational Site, Shanghai, , China
GSK Investigational Site, Tianjin, , China
GSK Investigational Site, Brno, , Czech Republic
GSK Investigational Site, Hradec Kralove, , Czech Republic
GSK Investigational Site, Praha 8, , Czech Republic
GSK Investigational Site, Cairo, , Egypt
GSK Investigational Site, Bayonne, , France
GSK Investigational Site, Bordeaux, , France
GSK Investigational Site, Clermont-Ferrand cedex, , France
GSK Investigational Site, Lille, , France
GSK Investigational Site, Lyon, , France
GSK Investigational Site, Marseille Cedex BP 156, , France
GSK Investigational Site, Mulhouse, , France
GSK Investigational Site, Paris Cedex 20, , France
GSK Investigational Site, Paris Cedex 5, , France
GSK Investigational Site, Saint-Cloud, , France
GSK Investigational Site, Saint-Herblain, , France
GSK Investigational Site, Tours, , France
GSK Investigational Site, Valenciennes, , France
GSK Investigational Site, Mannheim, Baden-Wuerttemberg, Germany
GSK Investigational Site, Ulm, Baden-Wuerttemberg, Germany
GSK Investigational Site, Aschaffenburg, Bayern, Germany
GSK Investigational Site, Muenchen, Bayern, Germany
GSK Investigational Site, Rosenheim, Bayern, Germany
GSK Investigational Site, Frankfurt, Hessen, Germany
GSK Investigational Site, Duisburg, Nordrhein-Westfalen, Germany
GSK Investigational Site, Essen, Nordrhein-Westfalen, Germany
GSK Investigational Site, Herne, Nordrhein-Westfalen, Germany
GSK Investigational Site, Troisdorf, Nordrhein-Westfalen, Germany
GSK Investigational Site, Velbert, Nordrhein-Westfalen, Germany
GSK Investigational Site, Witten, Nordrhein-Westfalen, Germany
GSK Investigational Site, Mainz, Rheinland-Pfalz, Germany
GSK Investigational Site, Lohsa, Sachsen, Germany
GSK Investigational Site, Zwickau, Sachsen, Germany
GSK Investigational Site, Pinneberg, Schleswig-Holstein, Germany
GSK Investigational Site, Berlin, , Germany
GSK Investigational Site, Berlin, , Germany
GSK Investigational Site, Athens, , Greece
GSK Investigational Site, Hong Kong, , Hong Kong
GSK Investigational Site, Sheung Wan, , Hong Kong
GSK Investigational Site, Tuen Mun, , Hong Kong
GSK Investigational Site, Petach Tikva, , Israel
GSK Investigational Site, Ramat Gan, , Israel
GSK Investigational Site, Rehovot, , Israel
GSK Investigational Site, Zrifin, , Israel
GSK Investigational Site, Milano, Lombardia, Italy
GSK Investigational Site, Sassari, Sardegna, Italy
GSK Investigational Site, Prato (PO), Toscana, Italy
GSK Investigational Site, Incheon City, , Korea, Republic of
GSK Investigational Site, seodaemun-gu, Seoul, , Korea, Republic of
GSK Investigational Site, songpa-gu, Seoul, , Korea, Republic of
GSK Investigational Site, Casablanca, , Morocco
GSK Investigational Site, Hassan Rabat, , Morocco
GSK Investigational Site, Rabat, , Morocco
GSK Investigational Site, Lahore, , Pakistan
GSK Investigational Site, Lahore, , Pakistan
GSK Investigational Site, Multan, , Pakistan
GSK Investigational Site, Lima, , Peru
GSK Investigational Site, Cebu, , Philippines
GSK Investigational Site, Manila, , Philippines
GSK Investigational Site, Quezon City, , Philippines
GSK Investigational Site, Sampaloc Manila, , Philippines
GSK Investigational Site, Bucuresti, , Romania
GSK Investigational Site, Cluj-Napoca, , Romania
GSK Investigational Site, Iasi, , Romania
GSK Investigational Site, Chelyabinsk, , Russian Federation
GSK Investigational Site, Kazan, , Russian Federation
GSK Investigational Site, Moscow, , Russian Federation
GSK Investigational Site, Ryazan, , Russian Federation
GSK Investigational Site, St. Petersburg, , Russian Federation
GSK Investigational Site, St. Petersburg, , Russian Federation
GSK Investigational Site, Singapore, , Singapore
GSK Investigational Site, Barcelona, , Spain
GSK Investigational Site, Barcelona, , Spain
GSK Investigational Site, Madrid, , Spain
GSK Investigational Site, Madrid, , Spain
GSK Investigational Site, Madrid, , Spain
GSK Investigational Site, Málaga, , Spain
GSK Investigational Site, Sevilla, , Spain
GSK Investigational Site, Valencia, , Spain
GSK Investigational Site, Valencia, , Spain
GSK Investigational Site, Changhua, , Taiwan
GSK Investigational Site, Taipei, , Taiwan
GSK Investigational Site, Tao-Yuan county, , Taiwan
GSK Investigational Site, Bangkok, , Thailand
GSK Investigational Site, Khon Kaen, , Thailand
GSK Investigational Site, Lampang, , Thailand
GSK Investigational Site, Phitsanulok, , Thailand
GSK Investigational Site, Ariana, Tunis, , Tunisia
GSK Investigational Site, Sfax, , Tunisia
GSK Investigational Site, Sousse, , Tunisia
GSK Investigational Site, Istanbul, , Turkey
GSK Investigational Site, Izmir, , Turkey
GSK Investigational Site, Northwood, Middlesex, United Kingdom
GSK Investigational Site, Bebington, Wirral, , United Kingdom
GSK Investigational Site, London, , United Kingdom
GSK Investigational Site, Sutton, , United Kingdom
Contact Details
Name: GSK Clinical Trials
Affiliation: GlaxoSmithKline
Role: STUDY_DIRECTOR
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