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Spots Global Cancer Trial Database for Pharmacokinetics And Pharmacodynamics Of Lapatinib In Two Dosing Regimens In Treatment-naive Patients With Breast Cancer

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Pharmacokinetics And Pharmacodynamics Of Lapatinib In Two Dosing Regimens In Treatment-naive Patients With Breast Cancer

Official Title: A Phase I, Open Label Study of the Safety, Pharmacokinetics and Pharmacodynamics of GW572016 in Once Daily Versus Twice Daily Dosing Regimens in Patients With Treatment- Naive Breast Cancer

Study ID: NCT00359190

Interventions

lapatinib

Study Description

Brief Summary: This study will examine the inhibition of ErbB1 and ErbB2 phosphorylation and downstream mediators of tumor cell growth and survival tumor tissue in treatment-naive breast cancer patients for three dosing schedules of lapatinib.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

GSK Investigational Site, Miami, Florida, United States

GSK Investigational Site, Durham, North Carolina, United States

GSK Investigational Site, Allentown, Pennsylvania, United States

GSK Investigational Site, Pittsburgh, Pennsylvania, United States

GSK Investigational Site, Nashville, Tennessee, United States

GSK Investigational Site, Dallas, Texas, United States

GSK Investigational Site, Roanoke, Virginia, United States

GSK Investigational Site, Milwaukee, Wisconsin, United States

GSK Investigational Site, Ramat Gan, , Israel

GSK Investigational Site, Zrifin, , Israel

Contact Details

Name: GSK Clinical Trials

Affiliation: GlaxoSmithKline

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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