Spots Global Cancer Trial Database for A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
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Trial Identification
Brief Title: A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Official Title: A Phase 2 Open-label Randomized Study of Farletuzumab Ecteribulin (MORAb-202), a Folate Receptor Alpha-targeting Antibody-drug Conjugate, Versus Investigator's Choice Chemotherapy in Women With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Study ID: NCT05613088
Conditions
Study Description
Brief Summary: The purpose of the study is to assess the safety, tolerability, and efficacy of farletuzumab ecteribulin (MORAb-202) and compare it to Investigator's choice (IC) chemotherapy in female participants with platinum-resistant HGS ovarian, primary peritoneal, or fallopian tube cancer.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Local Institution - 0040, Orange, California, United States
UC Davis Comprehensive Cancer Center, Sacramento, California, United States
UC Davis Comprehensive Cancer Center, Sacramento, California, United States
California Pacific Medical Center (CPMC) - Research Institute, San Francisco, California, United States
Local Institution - 0078, Whittier, California, United States
Local Institution - 0051, Aurora, Colorado, United States
Local Institution - 0024, Gainesville, Florida, United States
Local Institution - 0052, Chicago, Illinois, United States
Local Institution - 0081, South Bend, Indiana, United States
Local Institution - 0043, Kansas City, Kansas, United States
Corewell Health, Grand Rapids, Michigan, United States
Local Institution - 0041, Grand Rapids, Michigan, United States
Local Institution - 0034, Saint Louis, Missouri, United States
Local Institution - 0035, Bronx, New York, United States
Local Institution - 0067, Bronx, New York, United States
Local Institution - 0073, New York, New York, United States
Local Institution - 0063, New York, New York, United States
Columbia University Medical Center - Herbert Irving Pavilion Location, New York, New York, United States
Local Institution - 0062, New York, New York, United States
Local Institution - 0026, New York, New York, United States
Local Institution - 0028, Chapel Hill, North Carolina, United States
Local Institution - 0023, Canton, Ohio, United States
Local Institution - 0076, Columbus, Ohio, United States
Zangmeister Cancer Center, Columbus, Ohio, United States
Local Institution - 0044, Nashville, Tennessee, United States
Local Institution - 0050, Dallas, Texas, United States
Local Institution - 0082, Salt Lake City, Utah, United States
Providence Sacred Heart Medical Center & Children's Hospital, Spokane, Washington, United States
GenesisCare - North Shore, Sydney, New South Wales, Australia
Calvary Mater Newcastle, Waratah, New South Wales, Australia
Icon Cancer Centre - Chermside, Chermside, Queensland, Australia
Monash Medical Centre Clayton, Clayton, Victoria, Australia
Cabrini Hospital - Malvern, Malvern, Victoria, Australia
Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
Sir Charles Gairdner Hospital (SCGH) - WA Cancer Centre, Perth, Western Australia, Australia
Local Institution - 0032, Leuven, VBR, Belgium
Local Institution - 0013, Namur, WNA, Belgium
Local Institution - 0012, Brussels, , Belgium
Local Institution - 0033, Hasselt, , Belgium
Local Institution - 0045, Liège, , Belgium
Local Institution - 0059, Santiago, Metropolitana, Chile
Local Institution - 0030, Santiago, RM, Chile
Local Institution - 0060, Vina del Mar, Valparaiso, Chile
Local Institution - 0071, Vina Del Mar, Valparaiso, Chile
Oncovida - Santiago, Santiago, , Chile
Local Institution - 0029, Temuco, , Chile
Local Institution - 0046, Jerusaelm, JM, Israel
Local Institution - 0047, Tel-Aviv, Tel Aviv, Israel
Local Institution - 0054, Haifa, , Israel
Local Institution - 0080, Jerusalem, , Israel
Local Institution - 0055, Ramat Gan, , Israel
Local Institution - 0048, Tel Aviv-Yafo, , Israel
Local Institution - 0068, Tel Hashomer, , Israel
Local Institution - 0003, Bologna, BO, Italy
Local Institution - 0011, Milano, MI, Italy
Local Institution - 0009, Milano, MI, Italy
Local Institution - 0010, Roma, RM, Italy
Local Institution - 0008, Torino, TO, Italy
Local Institution - 0002, Brescia, , Italy
Hyogo Cancer Center, Akashi, Hyogo, , Japan
Local Institution - 0079, Akashi, , Japan
Local Institution - 0019, Chuo-Ku, , Japan
Local Institution - 0014, Hidaka-shi, , Japan
Local Institution - 0004, Kurume-Shi, , Japan
Local Institution - 0037, Tokyo, , Japan
Local Institution - 0064, Goyang-si, , Korea, Republic of
Local Institution - 0074, Goyang-si, , Korea, Republic of
Seoul National University Hospital, Jongno -Gu, , Korea, Republic of
Local Institution - 0056, Seoul, , Korea, Republic of
Yonsei University Health System, Severance Hospital, Seoul, , Korea, Republic of
Local Institution - 0057, Seoul, , Korea, Republic of
Local Institution - 0066, Seoul, , Korea, Republic of
Asan Medical Center (AMC), Seoul, , Korea, Republic of
Local Institution - 0039, Barcelona, B, Spain
Hospital General Universitario Gregorio Marañón, Madrid, M, Spain
Local Institution - 0001, Madrid, M, Spain
Local Institution - 0007, Valencia, V, Spain
Local Institution - 0006, Valencia, V, Spain
Local Institution - 0021, Barcelona, , Spain
Local Institution - 0020, Girona, , Spain
Local Institution - 0038, Madrid, , Spain
Local Institution - 0022, Madrid, , Spain
Contact Details
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR
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