Spots Global Cancer Trial Database for Prostate Cancer Study In Men Who Have Failed First-Line Androgen Deprivation Therapy
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Trial Identification
Brief Title: Prostate Cancer Study In Men Who Have Failed First-Line Androgen Deprivation Therapy
Official Title: A Randomized Double-Blind Parallel Group Study Comparing Casodex (or Generic Equivalent) 50mg Plus Placebo to Casodex (or Generic Equivalent) 50mg Plus Dutasteride 3.5mg Administered for 18 Months to Men With Prostate Cancer Who Have Failed First-Line Androgen Deprivation Therapy (Assessed by Rising PSA) Followed by a Two-Year Extension Phase
Study ID: NCT00470834
Conditions
Study Description
Brief Summary: Dutasteride inhibits the conversion of testosterone to dihydrotestosterone (DHT) the male hormone that leads to benign prostate growth. By blocking the conversion of testosterone to DHT, dutasteride could allow bicalutamide to be a more effective anti-androgen thus prolonging bicalutamide's efficacy.
Detailed Description:
Eligibility
Minimum Age: 40 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Locations
GSK Investigational Site, Homewood, Alabama, United States
GSK Investigational Site, Huntsville, Alabama, United States
GSK Investigational Site, Little Rock, Arkansas, United States
GSK Investigational Site, Anaheim, California, United States
GSK Investigational Site, Fresno, California, United States
GSK Investigational Site, San Bernardino, California, United States
GSK Investigational Site, San Diego, California, United States
GSK Investigational Site, Denver, Colorado, United States
GSK Investigational Site, Washington, District of Columbia, United States
GSK Investigational Site, Aventura, Florida, United States
GSK Investigational Site, Daytona Beach, Florida, United States
GSK Investigational Site, Orlando, Florida, United States
GSK Investigational Site, Galesburg, Illinois, United States
GSK Investigational Site, Evansville, Indiana, United States
GSK Investigational Site, Fort Wayne, Indiana, United States
GSK Investigational Site, Jeffersonville, Indiana, United States
GSK Investigational Site, Overland Park, Kansas, United States
GSK Investigational Site, New Orleans, Louisiana, United States
GSK Investigational Site, Shreveport, Louisiana, United States
GSK Investigational Site, Annapolis, Maryland, United States
GSK Investigational Site, Watertown, Massachusetts, United States
GSK Investigational Site, Chaska, Minnesota, United States
GSK Investigational Site, Minneapolis, Minnesota, United States
GSK Investigational Site, St. Louis, Missouri, United States
GSK Investigational Site, Omaha, Nebraska, United States
GSK Investigational Site, Las Vegas, Nevada, United States
GSK Investigational Site, Albany, New York, United States
GSK Investigational Site, Garden City, New York, United States
GSK Investigational Site, Manhasset, New York, United States
GSK Investigational Site, New York, New York, United States
GSK Investigational Site, Syracuse, New York, United States
GSK Investigational Site, Concord, North Carolina, United States
GSK Investigational Site, Columbus, Ohio, United States
GSK Investigational Site, Bala Cynwyd, Pennsylvania, United States
GSK Investigational Site, Lancaster, Pennsylvania, United States
GSK Investigational Site, Philadelphia, Pennsylvania, United States
GSK Investigational Site, Myrtle Beach, South Carolina, United States
GSK Investigational Site, Memphis, Tennessee, United States
GSK Investigational Site, Houston, Texas, United States
GSK Investigational Site, San Antonio, Texas, United States
GSK Investigational Site, Norfork, Virginia, United States
GSK Investigational Site, Richmond, Virginia, United States
GSK Investigational Site, Virginia Beach, Virginia, United States
GSK Investigational Site, Williamsburg, Virginia, United States
GSK Investigational Site, Seattle, Washington, United States
GSK Investigational Site, Seattle, Washington, United States
GSK Investigational Site, Milwaukee, Wisconsin, United States
GSK Investigational Site, Calgary, Alberta, Canada
GSK Investigational Site, Surrey, British Columbia, Canada
GSK Investigational Site, Victoria, British Columbia, Canada
GSK Investigational Site, Barrie, Ontario, Canada
GSK Investigational Site, Burlington, Ontario, Canada
GSK Investigational Site, North Bay, Ontario, Canada
GSK Investigational Site, Oakville, Ontario, Canada
GSK Investigational Site, Scarborough, Ontario, Canada
GSK Investigational Site, Sudbury, Ontario, Canada
GSK Investigational Site, Toronto, Ontario, Canada
GSK Investigational Site, Toronto, Ontario, Canada
GSK Investigational Site, Greenfield Park, Quebec, Canada
GSK Investigational Site, Laval, Quebec, Canada
GSK Investigational Site, Pointe-Claire, Quebec, Canada
GSK Investigational Site, Quebec, , Canada
Contact Details
Name: GSK Clinical Trials
Affiliation: GlaxoSmithKline
Role: STUDY_DIRECTOR
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