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Brief Title: An Investigational Drug, Crizotinib (PF-02341066), Is Being Studied In Tumors, Except Non-Small Cell Lung Cancer, That Are Positive For Anaplastic Lymphoma Kinase (ALK)
Official Title: PHASE 1B OPEN-LABEL STUDY OF THE SAFETY AND CLINICAL ACTIVITY OF CRIZOTINIB (PF-02341066) IN TUMORS WITH GENETIC EVENTS INVOLVING THE ANAPLASTIC LYMPHOMA KINASE (ALK ) GENE LOCUS
Study ID: NCT01121588
Brief Summary: This is a Phase 1 trial evaluating the safety and efficacy of crizotinib in patients with tumors except non-small cell lung cancer that are positive for ALK.
Detailed Description:
Minimum Age: 15 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Highlands Oncology Group, Fayetteville, Arkansas, United States
Highlands Oncology Group, Rogers, Arkansas, United States
Highland Oncology Group, Springdale, Arkansas, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
OHSU Center for Health and Healing 2, Portland, Oregon, United States
Oregon Health & Science University, Portland, Oregon, United States
Oregon Health and Science University, Portland, Oregon, United States
Greenville Health System, Institute for Translational Oncology Research, Greenville, South Carolina, United States
Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, Chaoyang District, China
SUN Yat-Sen University Cancer Center, Guangzhou, Guangdong, China
Centro di Ricerca di Fase 1 ASST-Monza, Monza, , Italy
PO San Gerardo, ASST Monza-U.O Ematologia, Monza, , Italy
National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan
National Cancer Center Hospital, Chuo-ku, Tokyo, Japan
National Hospital Organization Kyushu Cancer Center, Fukuoka, , Japan
Seoul National University Hospital, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
GBOU VPO "First Saint-Petersburg State Medical University n.a.I.P Pavlov" Ministry of Health, Saint-Petersburg, , Russian Federation
Institute of Pedriatric Oncology, Hematology and Transplantation n.a R.M Gorbacheva, Saint-Petersburg, , Russian Federation
National Taiwan University Hospital, Department of Internal Medicine, Taipei, , Taiwan
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR