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Brief Title: Evaluate the Efficacy of Magnesium Isoglycyrrhizinate in the Prevention of Chemotherapy Related Acute Liver Injury
Official Title: A Randomized, Controlled, Multi-center Collaborative Study to Evaluate the Efficacy of Magnesium Isoglycyrrhizinate Injection in the Prevention of Antineoplastic Chemotherapy Related Acute Liver Injury
Study ID: NCT01802996
Brief Summary: This purpose of this study is to evaluate the evaluate the efficacy of Magnesium Isoglycyrrhizinate Injection in the prevention of antineoplastic chemotherapy related acute liver injury.
Detailed Description: Total subjects: 2040, experimental group of 1360 patients, control group of 680 patients. According to the study subjects receiving antineoplastic chemotherapy, subjects are stratified randomize.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, Anhui, China
China PLA General Hospital, Beijing, Beijing, China
The First Affiliated Hospital of General Hospital of PLA ( 304 ), Beijing, Beijing, China
Fujian Province-owned Hospital, Fuzhou, Fujian, China
Fuzhou General Hospital of Nanjing Military Area Command, Fuzhou, Fujian, China
Guangdong General Hospital, Guangzhou, Guangdong, China
The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong, China
Tumour Hospital Affiliated to Guangzhou Medical College, Guangzhou, Guangdong, China
The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China
The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
The first hospital of Hebei Medical University, Shijiazhuang, Hebei, China
The second hospital of Hebei Medical University, Shijiazhuang, Hebei, China
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
The people's Hospital of Wuhan University, Wuhan, Hubei, China
Xiangya Hospital of Central South University, Changsha, Hunan, China
Changzhou Second People's Hospital, Changzhou, Jiangsu, China
The 81st hospital of PLA, Nanjing, Jiangsu, China
Nanjing General Hospital of Nanjing Military Area Command, Nanjing, Jiangsu, China
The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
The first hospital of Nanjing, Nanjing, Jiangsu, China
The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
Wuxi Fourth People's Hospital, Wuxi, Jiangsu, China
Wuxi People's Hospital, Wuxi, Jiangsu, China
Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu, China
The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
Affiliated Hospital of Medical College of Qiingdao University, Qingdao, Shandong, China
The First Affiliated Hospital of Xinjiang Medical University, Wulumuqi, Xinjiang, China
Name: Qin Shukui, MD
Affiliation: The 81st hospital of PLA
Role: PRINCIPAL_INVESTIGATOR