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Brief Title: Imaging and Biomarkers of Hypoxia in Solid Tumors
Official Title: Imaging and Biomarkers of Hypoxia in Solid Tumors
Study ID: NCT01123005
Brief Summary: Hypoxia, meaning a lack of oxygen, has been associated strongly with a wide range of human cancers. Hypoxia occurs when tumor growth exceeds the ability of blood vessels to supply the tumor with oxygenated blood. It is currently understood that hypoxic tumors are more aggressive. Current methods for measuring hypoxia include invasive procedures such as tissue biopsy, or insertion of an electrode into the tumor. EF5-PET may be a non-invasive way to measure tumor hypoxia.
Detailed Description: To establish PET imaging with the tracer EF5 as an accurate and reliable method for measuring the oxygen content of a tumor and to establish the measurement of secreted markers in blood as an accurate and reliable method for measuring the oxygen content of a tumor.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Stanford University School of Medicine, Stanford, California, United States
Name: Dr. Billy W. Loo Jr. M.D. Ph.D.
Affiliation: Stanford University
Role: PRINCIPAL_INVESTIGATOR