Spots Global Cancer Trial Database for Beyond TME Origins

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Trial Identification

Brief Title: Beyond TME Origins

Official Title: Investigating the Origins of Pelvic Recurrence in Colorectal Cancer

Study ID: NCT02292641

Conditions

Neoplasms

Adenocarcinoma

Carcinoma

Interventions

New Radiological Staging Classification system for patients with advanced and recurrent colorectal cancer undergoing pelvic exenterative surgery

Study Description

Brief Summary: All patients with recurrent colorectal cancer in the pelvis are eligible. The original primary tumour staging scans and resected surgical specimen needs to be available. Patients' recurrence will be staged using our proposed MRI classification. We will be assessing the original primary staging scans and histopathology to learn about risk factors for recurrence. We will record treatment for the recurrence, and patients will be followed up for three years.

Detailed Description: A prospective and retrospective cohort study to improve surgical and treatment planning using an imaging assessment proforma of advanced and recurrent colorectal cancers. This involves the implementation of imaging assessment proformas describing anatomic pelvic compartments and aetiology of disease recurrence for treatment planning.