Spots Global Cancer Trial Database for First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
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Trial Identification
Brief Title: First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
Official Title: A Phase 1 First-Time-in-Human, Open-Label Study of GSK4381562 Administered as Monotherapy and in Combination With Anticancer Agents in Participants With Selected Advanced Solid Tumors
Study ID: NCT05277051
Conditions
Study Description
Brief Summary: This is a first time in-human (FTIH) study designed to investigate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of GSK4381562 in participants with select loco-regionally recurrent solid tumors or metastatic solid tumors where curative or standard treatment options have been exhausted.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
GSK Investigational Site, San Francisco, California, United States
GSK Investigational Site, Charlotte, North Carolina, United States
GSK Investigational Site, Oklahoma City, Oklahoma, United States
GSK Investigational Site, Philadelphia, Pennsylvania, United States
GSK Investigational Site, Dallas, Texas, United States
GSK Investigational Site, San Antonio, Texas, United States
GSK Investigational Site, Salt Lake City, Utah, United States
GSK Investigational Site, Nedlands, Western Australia, Australia
GSK Investigational Site, Ottawa, Ontario, Canada
GSK Investigational Site, Toronto, Ontario, Canada
GSK Investigational Site, Shnghai, , China
GSK Investigational Site, Dijon, , France
GSK Investigational Site, Lille, , France
GSK Investigational Site, Chiba, , Japan
GSK Investigational Site, Tokyo, , Japan
GSK Investigational Site, Seoul, , Korea, Republic of
GSK Investigational Site, Seoul, , Korea, Republic of
GSK Investigational Site, Barcelona, , Spain
GSK Investigational Site, Madrid, , Spain
GSK Investigational Site, Madrid, , Spain
GSK Investigational Site, Málaga, , Spain
GSK Investigational Site, Manchester, , United Kingdom
GSK Investigational Site, Sutton, , United Kingdom
Contact Details
Name: GSK Clinical Trials
Affiliation: GlaxoSmithKline
Role: STUDY_DIRECTOR
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