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Brief Title: Study Evaluating MST-997 in Advanced Malignant Solid Tumors
Official Title: A Phase 1 Dose-Escalation Study of Intravenous MST-997 Formulated in Polysorbate 80 Diluent Administered Weekly in Subjects With Advanced Malignant Solid Tumors
Study ID: NCT00277836
Brief Summary: MST-997 is a taxane analog with the potential to treat subjects with a variety of tumor types. Preclinical data demonstrated that MST-997 inhibited tumor growth when administered intravenously (IV). This phase 1 dose escalation study is designed to evaluate the safety and tolerability of if IV MST-997 formulated in Polysorbate 80 Diluent can be safely administered on a weekly basis.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Houston, Texas, United States
Name: Medical Monitor
Affiliation: Wyeth is now a wholly owned subsidiary of Pfizer
Role: STUDY_DIRECTOR
Name: Trial Manager
Affiliation: For Poland, WPWZMED@wyeth.com
Role: PRINCIPAL_INVESTIGATOR
Name: Trial Manager
Affiliation: For Netherlands, trials-NL@wyeth.com
Role: PRINCIPAL_INVESTIGATOR