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Spots Global Cancer Trial Database for Tumor-educated Platelets in Venous Thromboembolism

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Tumor-educated Platelets in Venous Thromboembolism

Official Title: Platelet RNA Profiling to Detect Occult Cancer in Patients With Unprovoked Venous Thromboembolism

Study ID: NCT02739867

Interventions

Study Description

Brief Summary: Among patients with a first episode of unprovoked venous thromboembolism (VTE), the contemporary one-year risk of detecting occult cancer is approximately 4% to 7%. Of these cases, 30% to 60% are missed by routine limited screening for cancer. RNA profiling of platelets is a promising, highly accurate biomarker for cancer detection, but its clinical utility in patients with unprovoked VTE is unknown. The objective of the present study is to evaluate the diagnostic accuracy of platelet RNA profiling in detecting occult cancer in patients with unprovoked venous thromboembolism. Secondary objectives include evaluation of other biomarkers for cancer, prediction of bleeding, and prediction of recurrent VTE.

Detailed Description:

Eligibility

Minimum Age: 40 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

KU Leuven, Leuven, , Belgium

Ottawa Hospital, Ottawa, , Canada

Dresden University Clinic, Dresden, , Germany

Bologna University Hospital, Bologna, , Italy

Gabriele D'Annunzio University, Chieti, , Italy

University of Padua, Padua, , Italy

University of Insubria, Varese, , Italy

Academic Medical Center, Amsterdam, Noord-Holland, Netherlands

Flevoziekenhuis, Almere, , Netherlands

Slotervaartziekenhuis, Amsterdam, , Netherlands

VU medical center, Amsterdam, , Netherlands

Tergooiziekenhuizen, Hilversum, , Netherlands

Leiden University Medical Center, Leiden, , Netherlands

Hospital Universitario Virgen del Rocio, Sevilla, , Spain

Contact Details

Name: Harry Büller, MD, PhD

Affiliation: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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