Spots Global Cancer Trial Database for Study of Anastrozole +/- AZD8931 in Postmenopausal Women With Endocrine Therapy Naive Breast Cancer
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Trial Identification
Brief Title: Study of Anastrozole +/- AZD8931 in Postmenopausal Women With Endocrine Therapy Naive Breast Cancer
Official Title: A Phase II, Randomised, Double-blind, Placebo-controlled, Multi-centre Study to Assess the Efficacy and Safety of AZD8931 In Combination With Anastrozole, Compared to Anastrozole Alone, in Post Menopausal Women With Hormone Receptor Positive, Endocrine Therapy Naive, Locally Advanced or Metastatic Breast Cancer (MINT).
Study ID: NCT01151215
Study Description
Brief Summary: The main purpose of this study is to compare progression free survival in patients treated with AZD8931 given in combination with anastrozole versus anastrozole alone. The secondary objective is to investigate the safety and tolerability of AZD8931 given in combination with anastrozole.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Research Site, Lake Success, New York, United States
Research Site, Belo Horizonte, , Brazil
Research Site, Goiânia, , Brazil
Research Site, Ijuí, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Rio de Janeiro, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, São Paulo, , Brazil
Research Site, Vancouver, British Columbia, Canada
Research Site, Ottawa, Ontario, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Brno, , Czech Republic
Research Site, Olomouc, , Czech Republic
Research Site, Praha 2, , Czech Republic
Research Site, Praha 4, , Czech Republic
Research Site, Helsinki, , Finland
Research Site, Tampere, , Finland
Research Site, Turku, , Finland
Research Site, Bangalore, , India
Research Site, Hyderabad, , India
Research Site, Mumbai, , India
Research Site, Pune, , India
Research Site, Trivandrum, , India
Research Site, Vellore, , India
Research Site, Niigata-shi, , Japan
Research Site, Osaka-shi, , Japan
Research Site, Ota-shi, , Japan
Research Site, Sapporo-shi, , Japan
Research Site, Seoul, , Korea, Republic of
Research Site, Durango, , Mexico
Research Site, Juchitan, , Mexico
Research Site, Merida, , Mexico
Research Site, Monterrey, , Mexico
Research Site, Callao, , Peru
Research Site, Lima, , Peru
Research Site, Piura, , Peru
Research Site, Iloilo City, , Philippines
Research Site, Lipa City, , Philippines
Research Site, Pasay City, , Philippines
Research Site, Quezon City, , Philippines
Research Site, Białystok, , Poland
Research Site, Elbląg, , Poland
Research Site, Kraków, , Poland
Research Site, Warszawa, , Poland
Research Site, Kuzmolovsky, , Russian Federation
Research Site, Moscow, , Russian Federation
Research Site, Saint Petersburg, , Russian Federation
Research Site, Durban, , South Africa
Research Site, Pretoria, , South Africa
Research Site, Taipei, , Taiwan
Research Site, Bangkok, , Thailand
Research Site, Songkla, , Thailand
Research Site, Dnipropetrovsk, , Ukraine
Research Site, Lviv, , Ukraine
Research Site, Birmingham, , United Kingdom
Research Site, Bournemouth, , United Kingdom
Research Site, Coventry, , United Kingdom
Research Site, Leicester, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Nottingham, , United Kingdom
Research Site, Surrey, , United Kingdom
Research Site, Wythenshawe, Manchester, , United Kingdom
Contact Details
Name: Dr Serban Ghiorghiu, MD
Affiliation: AstraZeneca
Role: STUDY_DIRECTOR
Name: Stephen Johnston, MA, PhD, FRCP
Affiliation: The Royal Marsden Hospital, London
Role: PRINCIPAL_INVESTIGATOR
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