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Brief Title: Effect of Itraconazole on the Pharmacokinetics of Apatinib
Official Title: Effect of Itraconazole on the Pharmacokinetics of Apatinib in Chinese Healthy Volunteers
Study ID: NCT02836171
Brief Summary: he primary purpose of this study is to investigate potential pharmacokinetic interaction in healthy volunteers when apatinib is administered in combination with itraconazole. Secondary objective is evaluating the safety and tolerability of apatinib alone and when co-administered with itraconazole.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: ALL
Healthy Volunteers: Yes
Shanghai Xuhui Central Hospital, Shanghai, Shanghai, China
Name: Chen Yu
Affiliation: Shanghai Xuhui Central Hospital
Role: PRINCIPAL_INVESTIGATOR