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Brief Title: A Study of E7386 in Combination With Other Anticancer Drug in Participants With Solid Tumor
Official Title: An Open-label Phase 1b Study of E7386 in Combination With Other Anticancer Drug(s) in Subjects With Solid Tumors
Study ID: NCT04008797
Brief Summary: The primary objective of this study is to assess the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of E7386 in combination with other anticancer drug(s).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of California San Diego (UCSD) - Moores Cancer Center(All), La Jolla, California, United States
Cedars-Sinai Medical Center, Los Angeles, California, United States
Pasadena Liver Center, Pasadena, California, United States
UCLA University of California - Los Angeles, Santa Monica, California, United States
University of Colorado Cancer Center - Anschutz Medical Campus, Aurora, Colorado, United States
Florida Cancer Specialists - South, Sarasota, Florida, United States
Florida Cancer Specialists - East, West Palm Beach, Florida, United States
Kansas City Research Institute, Kansas City, Missouri, United States
Perlmutter Cancer Center- NYU Langone Health, New York, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, United States
Medical University of South Carolina, Charleston, South Carolina, United States
Vanderbilt University Medical Center (VUMC) - Vanderbilt-Ingram Cancer Center (VICC) - Nashville, Nashville, Tennessee, United States
Mary Crowley Cancer Research, Dallas, Texas, United States
University of Texas Southwestern Medical, Dallas, Texas, United States
MD Anderson Cancer Center, Houston, Texas, United States
CHU Amiens-Picardie (Hopital Sud), Amiens, , France
Hôpital Beaujon, Clichy, , France
Centre Georges-François Leclerc, Dijon, , France
Grenoble University Hospital (Centre Hospitalier Universitaire Grenoble Alpes), La Tronche, , France
CHU de LILLE - Hôpital HURIEZ, Lille, , France
Hepatology, Hopital de la Croix-Rousse - 103 grande rue de la Croix-Rousse, Lyon, , France
APHP Hospital Saint-Antoine, Paris, , France
Centre Hospitalier Universitaire de Bordeaux (CHU Bordeaux)(Hopitaux de Bordeaux) - Groupe hospitalier Sud - Hopital Haut-Levequ, Pessac, , France
Gustave Roussy Institute (IGR), Villejuif, , France
Eisai Trial Site #5, Nagoya, Aichi, Japan
Eisai Trial Site #11, Toyoake, Aichi, Japan
Eisai Trial Site #2, Kashiwa, Chiba, Japan
Eisai Trial Site #8, Matsuyama, Ehime, Japan
Eisai Trial Site #7, Kurume, Fukuoka, Japan
Eisai Trial Site #10, Kawasaki, Kanagawa, Japan
Eisai Trial Site #12, Kamigyo-ku, Kyoto, Japan
Eisai Trial Site #3, Osakasayama, Osaka, Japan
Eisai Trial Site #9, Hidaka, Saitama, Japan
Eisai Trial Site #1, Chuo-Ku, Tokyo, Japan
Eisai Trial Site #6, Koto-ku, Tokyo, Japan
Eisai Trial Site #4, Chiba, , Japan
Eisai Trial Site #1, Seongnamsi Bundang, Gyeonggi-Do, Korea, Republic of
Eisai Trial Site #5, Jongno-gu, Seoul, Korea, Republic of
Eisai Trial Site #2, Seodaemun, Seoul, Korea, Republic of
Eisai Trial Site #4, Songpa-gu, Seoul, Korea, Republic of
Eisai Trial Site #3, Seoul, , Korea, Republic of
Chang Gung Medical Foundation - Kaohsiung Branch, Kao-Hsiung, , Taiwan
Taichung Veterans General Hospital, Taichung, , Taiwan
National Cheng Kung University Hospital, Tainan, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Taipei, , Taiwan
Chang Gung Medical Foundation - Linkou Branch, Taoyuan, , Taiwan