Spots Global Cancer Trial Database for Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome

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Trial Identification

Brief Title: Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome

Official Title: Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome

Study ID: NCT00588068

Conditions

Neuroblastoma

Interventions

Tumor and Marrow Markers

Study Description

Brief Summary: The purpose of this study is to find out the genetic and biochemical makeup of your neuroblastic tumor, which influences its aggressiveness and the suitable therapy. These research studies include surface marker analysis, cytogenetics, cancer genes,genome sequencing, tumor growth-related genes and tumor growth in test tubes. Your blood, marrow, and hematopoietic stem cell samples will also be tested for tumors or leukemia cells, and your serum tested for anti-tumor antibodies.

Detailed Description: To collect tumor, marrow specimens prospectively to study the molecular-genetic makeup of individual neuroblastic tumor and its metastasis by blood and marrow, and to correlate these findings with clinical outcome, and to relate the signaling circuitry of neuroblastic tumors to that of embryonic neuroectodermal cells. .