Spots Global Cancer Trial Database for Pediatric Precision Laboratory Advanced Neuroblastoma Therapy
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Trial Identification
Brief Title: Pediatric Precision Laboratory Advanced Neuroblastoma Therapy
Official Title: A Study Using Molecular Guided Therapy With Induction Chemotherapy Followed by a Randomized Controlled Trial of Standard Immunotherapy With or Without DFMO Followed by DFMO Maintenance for Subjects With Newly Diagnosed High-Risk Neuroblastoma
Study ID: NCT02559778
Conditions
Study Description
Brief Summary: A prospective open label, multicenter study to evaluate the feasibility and acute toxicity of using molecularly guided therapy in combination with standard therapy followed by a Randomized Controlled Trial of standard immunotherapy with or without DFMO followed by DFMO maintenance for Subjects with Newly Diagnosed High-Risk Neuroblastoma.
Detailed Description:
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Alabama, Children's of Alabama, Birmingham, Alabama, United States
Arkansas Children's Hospital, Little Rock, Arkansas, United States
UCSF Benioff Children's Hospital Oakland-, Oakland, California, United States
Rady Children's Hospital, San Diego, California, United States
Connecticut Children's Hospital, Hartford, Connecticut, United States
Nicklaus Children's Miami, Miami, Florida, United States
Arnold Palmer Hospital for Children, Orlando, Florida, United States
St. Joseph's Children's Hospital, Tampa, Florida, United States
Augusta University Health, Augusta, Georgia, United States
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii, United States
St. Lukes, Boise, Idaho, United States
Advocate Children's Medical Group, Chicago, Illinois, United States
University of Louisville, Louisville, Kentucky, United States
Helen DeVos Children's Hospital, Grand Rapids, Michigan, United States
Children's Hospital and Clinics of Minnesota, Minneapolis, Minnesota, United States
Children's Mercy Hospitals and Clinics, Kansas City, Missouri, United States
Cardinal Glennon Children's Medical Center, Saint Louis, Missouri, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Levine Children's Hospital, Charlotte, North Carolina, United States
Randall Children's Hospital, Portland, Oregon, United States
Penn State Milton S. Hershey Medical Center and Children's Hospital, Hershey, Pennsylvania, United States
Medical University of South Carolina, Charleston, South Carolina, United States
Dell Children's Blood and Cancer Center, Austin, Texas, United States
Children's Medical Center, Dallas, Texas, United States
Children's Hospital of The King's Daughters, Norfolk, Virginia, United States
UHC Sainte-Justine, Montréal, Quebec, Canada
Contact Details
Name: Giselle Sholler, MD
Affiliation: Beat Childhood Cancer
Role: STUDY_CHAIR
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