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Brief Title: Use of 68Ga-dotatate PET Scan in Neuroendocrine Carcinoma of the GI Tract
Official Title: Somatostatin Receptor Expression in Poorly-Differentiated Neuroendocrine Carcinomas of the GI Tract: Analysis Using 68Ga-dotatate PET Scan
Study ID: NCT04069299
Brief Summary: The purpose of the study is to understand the extent and degree of somatostatin receptor expression in poorly differentiated neuroendocrine carcinomas . This may help to make a determination if a radiolabeled somatostatin analog therapy, also referred to as peptide receptor radiotherapy (PRRT), can be a potential alternative in the future. At this time, radiolabeled somatostatin analogs have not been tested in patients with poorly differentiated neuroendocrine carcinomas, and their efficacy in this disease is not well known Understanding the extent and degree of somatostatin receptor expression is important in order to evaluate the potential of radiolabeled somatostatin analog therapy for treatment of poorly differentiated neuroendocrine carcinomas.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
H Lee Moffitt Cancer & Research Institute, Tampa, Florida, United States
Name: Jonathan Strosberg, MD
Affiliation: H Lee Moffitt Cancer & Research Institute
Role: PRINCIPAL_INVESTIGATOR