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Spots Global Cancer Trial Database for Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers

Official Title: Phase II Study of the Combination of Bevacizumab, Pertuzumab, and Sandostatin for Patients With Advanced Neuroendocrine Cancers.

Study ID: NCT01121939

Study Description

Brief Summary: The purpose of this Phase II trial will be to define the activity of a VEGF inhibitor bevacizumab, HER1/HER2 inhibitor pertuzumab, and sandostatin for patients with advanced neuroendocrine cancers. In particular, the efficacy of bevacizumab and pertuzumab treatment is of great interest. The primary endpoint of this trial will be response rate. Toxicity and progression-free survival will be obtained and evaluated.

Detailed Description: * To determine overall response rate of patients with low grade neuroendocrine cancer when treated with the combination of bevacizumab, pertuzumab and sandostatin LAR®. * To determine the disease control rate (objective response + stable disease), time to treatment progression, progression-free survival, and overall survival in patients with advanced low grade neuroendocrine cancer when treated with bevacizumab, pertuzumab and Sandostatin LAR® treatment. * To define the toxicity and safety of the combination of bevacizumab, pertuzumab and Sandostatin LAR® when used in patients with advanced low grade neuroendocrine cancer.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Florida Cancer Specialists, Fort Myers, Florida, United States

Florida Hospital Cancer Institute, Orlando, Florida, United States

Medical Oncology Associates of Augusta, Augusta, Georgia, United States

Baptist Medical Center East, Louisville, Kentucky, United States

Grand Rapids Oncology Program, Grand Rapids, Michigan, United States

Research Medical Center, Kansas City, Missouri, United States

Hematology-Oncology Associates of Northern NJ, Morristown, New Jersey, United States

Oncology Hematology Care, Inc, Cincinnati, Ohio, United States

Tennessee Oncology Associates, Nashville, Tennessee, United States

Contact Details

Name: Johanna C Bendell, S.B., M.D.

Affiliation: SCRI Development Innovations, LLC

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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